Advances in immunology. Volume 147 / edited by Frederick W. Alt. -- Amsterdam : Elsevier, c2020. – (58.691/A244/v.147)

Contents

Contributors
1. Histone deacetylases as targets in autoimmune and autoinflammatory diseases
    1. Introduction
    2. Basic aspects of the biology of HDACs
    3. Rheumatoid arthritis
    4. Inflammatory bowel diseases
    5. Multiple sclerosis
    6. Outlook
    Acknowledgments
    References
2. The role of NK cell as central communicators in cancer immunity
    1. NK cells in cancer
    2. NK cell cross-talk with innate immune cells
    3. Cross-talk of NK cells with adaptive immune cells
    4. Cross-talk of NK cell with stromal ceils
    5. Impairment of NK cell communication
    6. Concluding remarks
    Acknowledgments
    Conflict of interest
    References
3. Mechanism and regulation of class switch recombination by IgH transcriptional control elements
    1. Overview of class switch recombination
    2. Role of IgH transcriptional control elements
    3. Class switch recombination in the CH12F3 cell line
    4. Class switch recombination in developing B cells
    5. Mechanism and regulation of class switch recombination
    6. The IncCSRIgA locus
    7. Perspectives
    Acknowledgments
    Compliance with ethics guidelines
    References