Lipid signaling and metabolism / edited by James M. Ntambi. -- London : Academic Press, [2020]. – (59.5181/L764) |
Contents
Contributors xiii
Preface xix
1. Homeostatic control of membrane lipid biosynthesis in bacteria 1
2. Lipid trafficking and signaling in plants 23
3. Sex as a modulator of lipid metabolism and metabolic disease 45
4. Local interactions in the bone marrow microenvironment and their contributions to systemic metabolic processes 63
5. Lipids in the transcriptional regulation of adipocyte differentiation and metabolism 81
6. Lipid receptors and signaling in adipose tissue 99
7. Adipocyte lipolysis and lipid-derived metabolite signaling 115
8. Regulation of intracellular lipid storage and utilization 131
9. The lipid droplet as a signaling node 157
10. Lipid droplets in the immune response and beyond 173
11. Fatty acid mediators and the inflammasome 197
12. Identification and pathophysiological roles of LTB4 receptors BLT1 and BLT2 223
13. The forkhead box O family in insulin action and lipid metabolism 247
14. Interplays between nutritional and inflammatory signaling and fat metabolism in pathophysiology of NAFLD 273
15. Endocannabinoids: the lipid effectors of metabolic regulation in health and disease 297
16. Gut microbiota interaction in host lipid metabolism 321
17. Insights into the metabolism of lipids in obesity and diabetes 345
18. Lipid metabolic features of skeletal muscle in pathological and physiological conditions 359
19. Sphingolipid mediators of cell signaling and metabolism 385
20. Role of bile acid receptors in the regulation of cardiovascular diseases 413
21. Molecular mechanisms underlying effects of n-3 and n-6 fatty acids in cardiovascular diseases 427
22. Lipid metabolism and signaling in cancer 455
23. Altered lipid metabolic homeostasis in the pathogenesis of Alzheimer's disease 469
24. Role of Xenosterols in Health and Disease 505
25. Adipose tissue development and metabolic regulation 521
Index 535