International review of cell and molecular biology. volume 337 / edited by Lorenzo Galluzzi. -- Amsterdam : Academic Press, c2018. – (58.15/I61/v.337)

Contents

Contributors

1.  Karyosphere (Karyosome): A Peculiar Structure of the Oocyte Nucleus

     1. Introduction

     2. Karyosphere vs Karyosome: A Brief History of Discovery and Terminological Background

     3. Karyosphere With Capsule

     4. Karyosphere Without Capsule (the Karyosome)

     5. Closing Remarks

     Acknowledgments

     References

2.  Organoids for Modeling Genetic Diseases

     1. Introduction

     2. Genetic Disorders Modeled With Organoids

     3. Conclusions and Perspectives

     Acknowledgments

     References

3.  Lipid Droplets as Organelles

     1. Introduction

     2. LD Biogenesis

     3. LD Maturation and Heterogeneity

     4. LD Fusion and Fission

     5. Interactions Between LDs and Other Organelles

     6. LD Turnover

     7. Conclusions and Future Perspectives

     Acknowledgments

     References

4.  The Lymphatic Fluid

     1. Introduction

     2. Lymph Formation

     3. Lymph Circulation

     4. Lymph Proteomics

     5. The Lymph Peptidome

     6. Immunological Role of the Lymph-Carried Proteome and Peptidome

     References

5.  Apoptosis and Cancer: Force Awakens, Phantom Menace, or Both?

     1. Apoptosis vs Cancer--A New Hope

     2. Unleashing the Force--Apoptotic Signaling Pathways

     3. Cancer Strikes Back Apoptosis as an Oncogenic Driver

     4. Flying Casual: Nonlethal, Oncogenic Roles for Apoptotic Proteins

     5. Help Me Apoptosis. You Are My Only Hope: Targeting Oncogenic Effects of Apoptosis in Cancer Therapy

     6. Outlook

     Acknowledgments

     References

6.  Crosstalk of Autophagy and the Secretory Pathway and Its Role in Diseases

     1. The Secretory Pathway

     2. Autophagy

     3. The Link Between Autophagy and the Secretory Pathway

     4. Secretory Autophagy

     S. The Role of the Crosstalk Between Autophagy and Secretion in Diseases

     6. Concluding Remarks

     Acknowledgments

     References

7.  Intracellular Pressure: A Driver of Cell Morphology and Movement

     1. Introduction

     2. A Brief History of Intracellular Pressure

     3. Generation of Intracellular Pressure

     4. Cell Morphology and Pressure

     5. Dynamic Pressure and Migratory Plasticity

     6. Intranuclear Pressure

     7. Conclusions

Acknowledgments

References

Further Reading