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Bio- and multifunctional polymer architectures : preparation, analytical methods and applications / Brigitte Voit, Rainer Haag, Dietmar Appelhans, Petra B. Welzel. -- Hoboken, New Jersey : Wiley, 2016. – (82.3/V898) |
Contents
Preface
Acknowledgments
1 Introduction
1.1 What makes Polymers so Interesting?, 1
1.2 Macromolecular Engineering and Nanostructure Formation, 4
1.3 Specific Needs in Bionanotechnology and Biomedicine, 5
Reference, 6
2 Terminology
2.1 Polymer Architectures, 7
2.2 Multifunctionality, 11
2.3 Bioconjugates, 12
2.4 Biocompatibility, 12
2.5 Biodegradation, 14
2.6 Bioactivity, 14
2.7 Multivalency, 15
2.8 Bionanotechnology, 17
References, 18
3 Preparation Methods and Tools
3.1 General Aspects of Polymer Synthesis, 19
3.2 Controlled Polymer Synthesis, 25
3.3 Effective Polymer Analogous Reactions, 43
3.4 Pegylation, 47
3.5 Bioconjugation, 51
3.6 Enzymatic Polymer Synthesis, 59
3.7 Solid Phase Synthesis and Biotechnological Approaches, 63
3.8 Hydrogels and Hydrogel Scaffolds, 81
3.9 Surface Modification and Film Preparation, 92
3.10 Microengineering of Polymers and Polymeric Surfaces, 102
References, 107
4 Analytical Methods
4.1 Molecular Structure and Molar Mass Determination of Polymers and Biohybrids, 113
4.2 Characterization of Aggregates and Assemblies, 137
4.3 Characterization of Hydrogel Networks, 147
4.4 Surface Characterization, 154
4.5 Biophysical Characterization and Biocompatibility, 166
5 Multifunctional Polymer Architectures
5.1 Multifunctional (Block) Copolymers, 187
5.2 Dendritic Polymers, 196
5.3 Glycopolymers, 203
5.4 Peptide-Based Structures, 212
5.5 Biohybrid Hydrogels, 224
6 Functional Materials and Applied Systems
6.1 Organic Nanoparticles and Aggregates for Drug and Gene Delivery, 241
6.2 Polymer Therapeutics and Targeting Approaches, 264
6.3 Multi- and Polyvalent Polymeric Architectures, 271
6.4 Bioresponsive Networks, 280
6.5 Biofunctional Surfaces, 284
Abbreviations
Index
