Genetics : genes, genomes, and evolution / Philip Meneely ... [et al]. -- Oxford : Oxford University Press, c2017 .—(58.14 /M541)

Contents

Preface  xiii

Teaching and Learning with Genetics: Genes, Genomes, and Evolution xviii

Support Package xxi

About the Authors of Genetics: Genes, Genomes, and Evolution xxii

Manuscript reviewers xxiii

Prologue 1

1 Evolution, Genomes, and Genetics  13

2 The Central Dogma of Molecular Biology  28

3 Genome Structure, Organization, and Variation  72

4 Descent with Modification: Continuity and Variation in the Genome 129

5 The Inheritance of Single-gene Traits  189

6 The Cellular Basis for Mendelian Genetics  219

7 X-linked Genes and Sex Chromosomes  264

8 The Inheritance of Multiple Genes  308

9 The Locations of Genes on Chromosomes: Linkage and Genetic Maps  341

10 Human Genetic Mapping, Genome-wide Association Studies, and Complex Traits  383

11 Exchange and Evolution  419

12 Transcription: Reading and Expressing Genes  464

13 Translation: From Nucleic Acids to Amino Acids  517

14 Networks of Gene Regulation  555

15 Genetic Analysis of Cellular Processes  597

16 The Genetics of Populations  642

17 Metagenomes: Genome Analysis of Communities  698

Glossary 728

Index 745