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Molecular biology of the gene / James D. Watson ... [et al.]. -- 7th ed. -- Boston : Pearson, 2014. – (58.1573 /W339 /7th ed.)

Contents

PART 1 HISTORY, 1

Brief Contents

1 The Mendelian View of the World, 5

2 Nucleic Acids Convey Genetic Information, 21

PART 2 STRUCTURE AND STUDY OF MACROMOLECULES, 45

3 The Importance of Weak and Strong Chemical Bonds, 51

4 The Structure of DNA, 77

5 The Structure and Versatility of RNA, 107

6 The Structure of Proteins, 121

7 Techniques of Molecular Biology, 147

PART 3 MAINTENANCE OF THE GENOME, 193

8 Genome Structure, Chromatin, and the Nucleosome, 199

9 The Replication of DNA, 257

10 The Mutability and Repair of DNA, 313

11 Homologous Recombination at the Molecular Level, 341

12 Site-Specific Recombination and Transposition of DNA, 377

PART 4 EXPRESSION OF THE GENOME, 423

13 Mechanisms of Transcription, 429

14 RNA Splicing, 467

15 Translation, 509

16 The Genetic Code, 573

17 The Origin and Early Evolution of Life, 593

PART 5 REGULATION, 609

18 Transcriptional Regulation in Prokaryotes, 615

19 Transcriptional Regulation in Eukaryotes, 657

20 Regulatory RNAs, 701

21 Gene Regulation in Development and Evolution, 733

22 Systems Biology, 775

PART 6 APPENDICES, 793

1 Model Organisms, 797

2 Answers, 831

Index, 845