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International review of cell and molecular biology. Volume 319 / edited by Kwang W. Jeon. -- Amsterdam : Academic Press, c2015. – (58.15/I61/v.319)

Contents

Contributors

1. From Single Cells to Engineered and Explanted Tissues: New Perspectives in Bacterial Infection Biology

1. introduction

2. 2D Cell Culture

3. 3D Cell Culture

4. Organ Equivalents and Tissue Explants

5. Concluding Remarks and Future Perspectives

Acknowledgments

References

2. Science and Art of Cell-Based Ocular Surface Regeneration        45

1. introduction

2. Anatomy and Pathology of Ocular Surface

3. Cell-Based Therapies for Ocular Surface Regeneration

4. New Material Technologies for Ocular Surface Reconstruction

5. Animal Models for LSCD

6. Clinical Outcome of Cell-Based Ocular Surface Reconstructive Procedure

7. Future Path and Conclusion

Acknowledgments

References

3. Eukaryotic Ribosome Assembly and Nuclear Export

1. Introduction

2. Assembly of 90S Preribosome, Earliest Ribosomal Precursor

3. Nuclear Maturation of Preribosomal Particles

4. Export of Preribosomal Subunits

5. Cytoplasmic Maturation of Preribosomal Particles

6. Concluding Remarks

References

4. Transmembrane 4 L Six Family Member 5 (TM4SF5)-Mediated EpitheliaI-Mesenchymal Transition in Liver Diseases

1. Introduction

2. TM4SF5 as Component of Tetraspanin-Enriched Microdomains

3. TM4SF5-Mediated EpitheliaI-Mesenchymal Transition

4. TM4SFS-Mediated Metastatic Potential

5. TM4SFS-Dependent Drug Resistance

6. TM4SF5-Dependent Self-Renewal Capacity

7. Conclusion

Acknowledgments

References

5. Emerging Roles of JmjC Domain-Containing Proteins

1. Introduction

2. Histone Modification and Methylation

3. Histone Demethylation and Demethylases

4. Plant JmjC Histone Demethylation

5. Conclusions

References

6. New Insight into the Role of Reactive Oxygen Species (ROS) in Cellular SignaI-Transduction Processes

1. Introduction

2. Background

3. Targets of Redox Regulation

4. Others

5. Pathophysiological Significance

6. Treatment Strategies Involving ROS Modulation

7. Measurement of ROS

8. Conclusions and Future Perspectives

References

7. Regeneration, Stem Cells, and Aging in the Tunicate Ciono: Insights from the Oral Siphon

1. Introduction

2. Background

3. OS Regeneration

4. Adult Stem Cells

5. Stem and Progenitor Cell Mobilization and Deployment

6. Aging and OS Regeneration

7. Concluding Remarks and Perspectives

Acknowledgments

References

Index