Basic immunology : functions and disorders of the immune system / Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai. -- 5th ed. -- St. Louis, Missouri : Elsevier, 2016. – (63.17/A122/5th ed.)

Contents

1  INTRODUCTION TO THE IMMUNE SYSTEM, 1

    Nomenclature, General Properties, and Components

2  INNATE IMMUNITY, 27

    The Early Defense Against Infections

3  ANTIGEN CAPTURE AND PRESENTATION TO LYMPHOCYTES, 55

    What Lymphocytes See

4  ANTIGEN RECOGNITION IN THE ADAPTIVE IMMUNE SYSTEM, 79

    Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires

5  T CELL-MEDIATED IMMUNITY, 103

    Activation of T Lymphocytes by Cell-Associated Antigens

6  EFFECTOR MECHANISMS OF T CELL-MEDIATED IMMUNITY, 129

    Functions of T Cells in Host Defense

7  HUMORAL IMMUNE RESPONSES, 147

    Activation of B Lymphocytes and Production of Antibodies

8  EFFECTOR MECHANISMS OF HUMORAL IMMUNITY, 169

    Elimination of Extracellular Microbes and Toxins

9  IMMUNOLOGICAL TOLERANCE AND AUTOIMMUNITY, 191

    Self-Nonself Discrimination in the Immune System and Its Failure

10  IMMUNE RESPONSES AGAINST TUMORS AND TRANSPLANTS, 211

      Immunity to Noninfectious Transformed and Foreign Cells

11  HYPERSENSITIVITY, 231

      Disorders Caused by Immune Responses

12  CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES, 249

      Diseases Caused by Defective Immunity

SELECTED READINGS, 267

APPENDIX I, 275

 Glossary

APPENDIX II, 303

 Cytokines

APPENDIX III, 307

 Principal Features of Selected CD Molecules

APPENDIX IV, 315

 Clinical Cases

INDEX, 329