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International review of cell and molecular biology. v. 296 / edited by Kwang W. Jeon. — Amsterdam : Elsevier, c2012. – (58.15/I61/v.296)

Contents

    CONTENTS
    
    Contributors
    1. New Insights into the Mechanism of Lens Development Using Zebra Fish
    1. Introduction
    2. Lens Developmental Stages
    3. Structural Components of the Lens
    4. Concluding Remarks
    References
    2. The Subcommissural Organ and the Development of the Posterior Commissure
    1. Introduction
    2. Axon Guidance and the Development of Commissures
    3. Posterior Commissure Development
    4. The Subcommissural Organ as a Specialized Ependyma
    5. SCO-Spondin as an Axonal Guidance Molecule
    6. Expression of Axonal Guidance Molecules in the Subcommissural Organ
    7. Subcommissural Organ-Posterior Commissure Alterations in Mutant Models
    8. Concluding Remarks
    Acknowledgments
    References
    3. Hypoxia and Hypoxia Signaling in Tissue Repair and Fibrosis
     1. Introduction
     2. Oxygen and Cellular Functions
     3. Hypoxia-Inducible Factor-1
     4. Skin Wound Repair and Acute Hypoxia
    5. Aberrant Wound Repair and Chronic Hypoxia
    6. Manipulating Hypoxia Signaling Pathway: Potential for Therapy
    7. Concluding Remarks
    References
    4. Factors Involved in Signal Transduction During Vertebrate Myogenesis
    1. Introduction
    2. Cells Involved in Myogenesis
    3. Signal Transduction in Cardiac Myogenesis
    4. Genes Involved in Skeletal Muscle Development
    5. Signal Transduction in the Development of SMs
    6. Regulatory ncRNAs in Muscle Development
    7. Concluding Remarks
    Acknowledgments
    References
    5. Biological Effects of Lysophosphatidic Acid in the Nervous System
    1. Introduction
    2. LPA: Metabolism and Signaling
    3. LPA Receptor Expression in the Developing and Adult Nervous System
    4. Cellular Effects of LPA in the Nervous System
    5. Physiological Effects of LPA in the Nervous System
    6. Therapeutic Intervention
    7. Concluding Remarks
    Acknowledgments
    References
    Index