Cell-cell junctions : a subject collection from Cold Spring Harbor perspectives in biology / edited by W. James Nelson, Elaine Fuchs. — Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c2010. – (58.15/C393u)

Contents

    Contents
    
    Preface
    Historical Perspective
    Discovering the Molecular Components of Intercellular Junctions--A Historical View
    Overview of Junction Organization
    Molecular Basis of the Core Structure of Tight Junctions， 35
    Adherens Junction: Molecular Architecture and Regulation， 49
    Gap Junctions， 63
    The Desmosome， 83
    Structural Organization of Junctions
    Structure and Biochemistry of Cadherins and Catenins， 101
    Physiology and Function of the Tight Junction， 123
    Junction Dynamics and Assembly
    Molecular Bases of Cell-Cell Junctions Stability and Dynamics， 139
    Intercellular Junction Assembly， Dynamics， and Homeostasis， 157
    Junction Signaling
    Adhesive and Signaling Functions of Cadherins and Catenins in Vertebrate Development
    Interplay of Cadherin-mediated Cell Adhesion and Canonical Wnt Signaling， 203
    Wnt Signaling from Development to Disease: Insights from Model Systems， 227
    Cadherin-mediated Intercellular Adhesion and Signaling Cascades Involving Small GTPases， 251
    Junctional Music that the Nucleus Hears: Cell-Cell Contact Signaling and the Modulation of Gene Activity， 265
    Complex Junction Organization
    Cell Adhesion， the Backbone of the Synapse: "Vertebrate" and "Invertebrate" Perspectives， 295
    Modular Design of Immunological Synapses and Kinapses， 321
    Membrane Domains Based on Ankyrin and Spectrin Associated with Cell-Cell Interactions， 337
    Planar Cell Polarity: Keeping Hairs Straight is Not So Simple， 355
    Junctions as Targets for Disease
    Listeria monocytogenes Internalin and E-cadherin: From Bench to Bedside， 371
    Cadherins as Targets for Genetic Diseases， 387
    Involvement of Members of the Cadherin Superfamily in Cancer， 407
    Index， 435