Intercellular communication in the nervous system / edited by Robert C. Malenka. — London : Academic, 2009. – (59.5911/I61) |
Contents
CONTENTS
Contributors
Contents
Preface
SECTION I: BASIC MECHANISMS OF SYNAPTIC TRANSMISSION (SYNAPTIC STRUCTURE AND ORGANIZATION)
Synaptic Precursors: Filopodia
Presynaptic Development: Functional and Morphological Organization
Postsynaptic Development: Neuronal Molecular Scaffolds
Dendrite Development, Synapse Formation and Elimination
Synapse Formation: Competition and the Role of Activity
Cell Adhesion Molecules at Synapses
Glia and Synapse Formation: An Overview
Active Zone
Calcium Channel Subtypes Involved in Neurotransmitter Release
SNAREs
Synaptic Vesicles
Endocytosis and Presynaptic Scaffolds
Postsynaptic Density/Architecture at Excitatory Synapses
Synaptic Transmission: Models
Glial Influence on Synaptic Transmission
Neurotransmitter Release from Astrocytes
Retrograde Transsynaptic Influences
Synaptic Plasticity: Short-Term Mechanisms
SECTION II: NEUROMUSCULAR AND GAP JUNCTIONS
Neuromuscular Connections: Vertebrate Patterns of
Neuromuscular Junction: Synapse Elimination
Presynaptic Events in Neuromuscular Transmission
Neuromuscular Junction (NMJ): Presynaptic Short-Term Plasticity of Neuromuscular Transmission
Neuromuscular Junction (NMJ): Postsynaptic Basal Lamina
Neuromuscular Junction (NMJ): Postsynaptic Events in Neuromuscular Transmission
Gap Junction Communication
Gap Junctions and Electrical Synapses
Gap Junctions and Hemichannels in Glia
Gap Junctions and Neuronal Oscillations
SECTION III: AMINO ACID TRANSMITTERS AND RECEPTORS
Glutamate
Glial Energy Metabolism: Overview
Transporter Proteins in Neurons and Glia
Vesicular Neurotransmitter Transporters
AMPA Receptors: Molecular Biology and Pharmacology
AMPA Receptor Cell Biology/Trafficking
NMDA Receptor Function and Physiological Modulation
NMDA Receptors, Cell Biology and Trafficking
Metabotropic Glutamate Receptors (mGluRs): Molecular Biology, Pharmacology and Cell Biology
Metabotropic Glutamate Receptors (mGluRs): Functions
Kainate Receptors: Molecular and Cell Biology
Kainate Receptor Functions
Long-Term Potentiation (LTP): NMDA Receptor Role
Long-Term Depression (LTD): Metabotropic Glutamate Receptor (mGluR) and NMDAR-Dependent Forms
D-Serine: From Its Synthesis in Glial Cell to Its Action on Synaptic Transmission and Plasticity
GABA Synthesis and Metabolism
GABAA Receptors: Molecular Biology, Cell Biology, and Pharmacology
GABAA Receptor Synaptic Functions
GABAB Receptors: Molecular Biology and Pharmacology
GABAB Receptor Function
Glycine Receptors: Molecular and Cell Biology
SECTION IV: AMINES AND ACETYLCHOLINE
Dopamine
Dopamine Receptors and Antipsychotic Drugs in Health and Disease
Dopamine: Cellular Actions
Noradrenaline
Norepinephrine: Adrenergic Receptors
Norepinephrine: CNS Pathways and Neurophysiology
Monoamines: Release Studies
Serotonin (5-Hydroxytryptamine; 5-HT): Neurotransmission and Neuromodulation
Serotonin (5-Hydroxytryptamine; 5-HT): Receptors
Serotonin (5-Hydroxytryptamine; 5-HT): CNS Pathways and Neurophysiology
Cholinergic Neurotransmission in the Autonomic and Somatic Motor Nervous System
Cholinergic Pathways in CNS
Muscarinic Receptors: Autonomic Neurons
Nicotinic Acetylcholine Receptors
SECTION V: NEUROPEPTIDES AND NEUROTROPHIC FACTORS
Neuropeptide Synthesis and Storage
Neuropeptide Release
Neuropeptides and Coexistence
Opioid Peptides and Receptors
Neuropeptide Y (NPY) and its Receptors
Corticotropin-Releasing Hormone and Urocortins: Binding Proteins and Receptors
Hypocretin/Orexin and MCH and Receptors
Peptidergic Receptors
Neuropeptides: Electrophysiology
Neurotrophins: Physiology and Pharmacology
Nerve Growth Factor
Retrograde Neurotrophic Signaling
BDNF in Synaptic Plasticity and Memory
GFL Neurotrophic Factors: Physiology and Pharmacology
Insulin-Like Growth Factor Signaling and Actions in Brain
Glial Growth Factors
SECTION VI: ATYPICAL NEUROTRANSMITTERS
Adenosine
Adenosine Triphosphate (ATP)
Purines and Purinoceptors: Molecular Biology Overview
P2X Receptors
Endocannabinoid Role in Synaptic Plasticity and Learning
Long-Term Depression (LTD): Endocannabinoids and Cerebellar LTD
Nitric Oxide
Role of NO in Neurodegeneration
Index