Signal transduction / Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E. R. Tatham. — 2nd ed. — Burlington, M.A. ; London : Elsevier/Academic Press, c2009. – (58.1574/G634/2nd ed.)

Contents

    Contents
    
    Preface xix
    Notes xxv
    Chapter 1: Prologue: Signal Transduction， Origins， and Ancestors 1
    Chapter 2: First Messengers 21
    Chapter 3: Receptors 37
    Chapter 4: GTP-binding Proteins and Signal Transduction
    Chapter 5: Effector Enzymes Coupled to GTP Binding Proteins: Adenylyl Cyclase and Phospholipase C
    Chapter 6: The Regulation of Visual Transduction and Olfaction 159
    Chapter 7: Intracellular Calcium 185
    Chapter 8: Calcium Effectors 221
    Chapter 9: Phosphorylation and Dephosphorylation: Protein kinases A and C 243
    Chapter 10: Nuclear Receptors 273
    Chapter 11: Growth Factors: Setting the Framework 297
    Chapter 12: Signalling Pathways Operated by Receptor Protein Tyrosine Kinases 315
    Chapter 13: Signal Transduction to and from Adhesion Molecules 375
    Chapter 14: Adhesion Molecules in the Regulation of Cell Differentiation: Mainly About Wnt 417
    Chapter 15: Activation of the Innate Immune System: the Toll-like Receptor 4 and Signalling through Ubiquitylation 451
    Chapter 16: Traffic of White Blood Cells 483
    Chapter 17: Tyrosine Protein Kinases and Adaptive Immunity: TCR， BCR， Soluble Tyrosine Kinases and NFAT 513
    Chapter 18: Phosphoinositide 3-Kinases， Protein Kinase B， and Signalling through the Insulin Receptor 543
    Chapter 19: Protein Kinase C Revisited 577
    Chapter 20: Signalling Through Receptor Serine/Threonine Kinases 599
    Chapter 21: Protein Dephosphorylation and Protein Phosphorylation 641
    Chapter 22: Notch 699
    Chapter 23: Targeting Transduction Pathways for Research and Medical Intervention 735
    Chapter 24: Protein Domains and Signal Transduction 763
    Index 791