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International review of cell and molecular biology. v. 278 / edited by Kwang W. Jeon. — Amsterdam : Elsevier, c2009. – (58.15/I61/v.278)

Contents

    CONTENTS
    
    Contributors
    1. Macromolecular Trafficking and Immune Evasion in African Trypanosomes
     1. General overview of the trypanosome life cycle
     2. Immune Evasion Mechanisms
     3. Endocytic Pathways
     4. Developmental Remodeling and Signaling
     5. Sorting Signals
     6. Secretory Protein Folding and Exocytosis
     7. Golgi Apparatus; Functions and Replication
     8. Ubiquitylation and Endocytosis of Trans-Membrane Domain Proteins
     9. Evolution of the Trypanosome Endomembrane System
     10. Conclusions and Future Perspectives
     Acknowledgments
     References
    2. Biological and Biophysical Properties of Vascular Connexin Channels
     1. Introduction
     2. The Vasculature
     3. Connexin Channels
     4. Gap Junctional Communication Pathways in the Vasculature
     5. Permeability of Vascular Connexin Channels
     6. Involvement of Connexins in Vascular Diseases
     7. Concluding Remarks
     Acknowledgments
     References
    3. Genotype-Phenotype Mapping: Developmental Biology Confronts the Toolkit Paradox
     1. Introduction
     2. Understanding the Genotype-Phenotype Relationship
     3. From Sequence to Form
     4. Beyond Sequence
     5. Case Study for Parsing Gene, Cell and Self-Organizing Roles in Morphogenesis
     6. Conclusion
     Acknowledgments
     References
    4. Role of Spindle Asymmetry in Cellular Dynamics
     1. Introduction
     2. Spindle Asymmetry and Control of Cell Cycle
     3. Spindle Asymmetry During Asymmetric Cell Divisions
     4. Concluding Remarks
     References
    5. Cell Adhesion in Amphibian Gastrulation
     1. Introduction
     2. Characteristics of Amphibian Gastrulation
     3. Gastrula Tissue as a Liquid: Cell Adhesion, Cell Sorting, Boundary Formation, and Tissue Positioning
     4. Collective Cell Migration, Cell Rearrangement, and Intercellular Migration
     5. Conclusion
     Acknowledgments
     References
    6. Molecular and Cell Biology of Testicular Germ Cell Tumors
     1. Introduction
     2. Epidemiology and Risk Factors
     3. Histopathology
     4. Prognostic and Diagnostic Markers
     5. Therapy
     6. Conclusions and Perspectives
     Acknowledgments
     References
    7. Polarity Proteins and Cell-Cell Interactions in the Testis
     1. Introduction
     2. Rho GTPases and Cell-Cell Interactions in the Testis: Cdc42
     3. Polarity Proteins and Cell-Cell Interactions in the Testis
     4. The Apical ES-BTB-Basement Membrane Functional Axis in the Seminiferous Epithelium that Coordinates the Cellular Events of Spermiation and BTB Restructuring During the Seminiferous Epithelial Cycle of Spermatogenesis: The Role of Polarity Proteins in Mediating the Apical ES-BTB-Basement Membrane Axis
     5. Roles of Polarity Proteins in Coordinating the Opposing Effects of Cytokines and Testosterone in Primary Preleptotene Spermatocyte Transit at the BTB
     6. Concluding Remarks and Future Perspectives
     Acknowledgment
     References
    Index