Tumor biomarker discovery : Methods and protocols / edited by Michael A. Tainsky. — New York, NY : Humana Press, 2009. – (58.17/M592/v.520)

Contents

    Contents
    
    1 Identification of Tumor-Associated Antigens as Diagnostic and Predictive Biomarkers in Cancer
    2 Autoantibodies Against Cancer Antigens
    3 Discovery of Antibody Biomarkers Using Protein Microarrays of Tumor Antigens Cloned in High Throughput
    4 Analysis of Glycans on Serum Proteins Using Antibody Microarrays
    5 Glycoproteomic Analysis by Two-Dimensional Electrophoresis
    6 All-Liquid Separations， Protein Microarrays， and Mass Spectrometry to Interrogate Serum Proteomes: An Application to Serum Glycoproteomics
    7 Reverse-Phase Protein Microarrays and Patient Tailored Therapy
    8 Serum Proteomics Using Mass Spectrometry
    9 Hormones as Biomarkers: Practical Guide to Utilizing Luminex Technologies for Biomarker Research 129
    10 High-Throughput Analysis of Serum Antigens Using Sandwich ELISAs on Microarrays
    11 Tissue Microarrays as a Tool in the Discovery and Validation of Tumor Markers
    12 Quantitative， Fluorescence-Based In Situ Assessment of Protein Expression 163
    13 Tumor Marker Discovery by Expression Profiling RNA from Formalin-Fixed Paraffin-Embedded Tissues 177
    14 High-Throughput Mutation Screening Using a Single Amplification Condition
    15 DNA Sequencing of Cancer-Related Genes for Biomarker Discovery
    16 Analysis of Loss of Heterozygosity in Circulating DNA
    17 Pharmacogenomics
    18 Study Designs in Genetic Epidemiology
    19 Developing Classifiers for the Detection of Cancer Using Multianalytes
    20 Metabolomics of Cancer
    21 MRI and MRS of Human Brain Tumors
    22 Magnetic Resonance Spectroscopy of Living Tissues 315
    Index