International review of cell and molecular biology / edited by Kwang W. Jeon. — Amsterdam : Elsevier, c2008. — (58.15/I61/v.271)

Contents

    CONTENTS
    
    Contributors
    1. Genetic Models of Cancer in Zebrafish
     1. Introduction
     2. Molecular Relevance of Zebrafish Cancer to Human Disease
     3. Forward Genetic Screens
     4. Targeted Cancer Models in Zebrafish
     5. Xenotransplantation
     6. Chemical Genetics: Small-Molecule Screening in Zebrafish
     7. Summary
     References
    2. Cellular and Molecular Biological Aspects of Cervical IntraepitheUal Neoplasia
     1. Introduction
     2. Cervical Cancer as a Unique Model of Human Carcinogenesis
     3. Biology of Cervical Neoplasias
     4. Cellular Aspects of Cervical Tumors Progression
     5. Molecular Aspects of Cervical Carcinogenesis
     6. Conclusions
     References
    3. Vesicle， Mitochondrial， and Plastid Division Machineries with Emphasis on Dynamin and Electron-Dense Rings 97
     1. Introduction
     2. Structural Similarities Among Mitochondrial， Plastid， and Vesicle Division Machineries
     3. Vesicle Division Machinery
     4. Bacterial， Microbody (Peroxisome)， Mitosome， and Hydrogenosome Division Machineries
     5. Mitochondrial Division Machinery
     6. Plastid (Chloroplast) Division Machinery
     7. Isolation of Organelle Division Machinery and Its Significance
     8. Concluding Remarks
     References
    4. Retromer: Multipurpose Sorting and Specialization in Polarized Transport
     1. Introduction: Basic Concepts on Coat-Mediated Vesicular Transport
     2. Retromer's Assembly and Functioning
     3. Multiple Roles of Retromer: Models of Study
     4. Polarized Transport Mediated by Retromer
     5. Implication of Retromer and Sorting Nexins in Other Aspects of Polarity
     6. Concluding Remarks
     References
    5. Translationa!Control of Gene Expression: From Transcripts to Transcriptomes 199
     1. Introduction
     2. Preparation for Translation: RNA Processing and Export
     3. Regulation of Translation
     4. Emerging Concepts in Translational Regulation
     5. Global Approaches to Identify Targets of Posttranscriptional Gene Regulation
     6. Concluding Remarks
     References
    6. Phagocytosis and Host-Pathogen Interactions in Dictyostelium with a Look at Macrophages 253
     1. Introduction
     2. The Dynamics of Phagocytosis
     3. Cellular Mechanisms of Phagocytosis
     4. Regulatory Pathways Controlling Phagocytosis
     5. Host-Pathogen Interactions: A Versatile New Model Host
     6. Concluding Remarks
     References
    7. Mechanobiolosy of Adult and Stem Cells
     1. Introduction
     2. Application of External Mechanical Forces to Cells
     3. Cell-Generated Mechanical Forces
     4. Mechanobiological Responses of Cells
     5. Mechanotransduction Mechanisms
     6. Concluding Remarks
     References
    Index