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Susceptibility to infectious diseases : the importance of host genetics / edited by Richard Bellamy. -- (Adavnces in molecular and microbiology ; 4). -- Cambridge University Press, 2004

Contents

索书号:63.86/S964

1. Introduction  1

2. Application of genetic epidemiology to dissecting host susceptibility/resistance to infection illustrated with the study of common mycobacterial infections  7

3. The Diverse genetic basis of immunodeficiencies  45

4. Genetic diversity in the major histocompatibility complex and the immune response to infectious diseases  77

5. The cystic fibrosis transmembrane conductance regulator  117

6. The influence of inherted traits on malaria infection  139

7. Polymorphica chemokine receptor and ligand genes in HIV infection  185

8. NRAMP1 and resistance to intracellular pathogens  221

9. The interleukin-12/interferon-γ loop is required for protective immunity to experimental and natural infections by Mycpbacterium  259

10. Mannose-binding lectin deficiency and susceptibility to infectious disease  279

11. Blood group phenotypes and infectious diseases  309

12. Genetics of human susceptibility to infection and hepatic disease caused by schistosomes  337

13. Genetic susceptibility to prion diseases  361