Biotechnology Annual Review. v.9 / edited by M. Raafat El-Gewely. -- Elsevier, 2003

Contents

1. Biochips beyond DNA: technologies and applications  1

2. Non-ribosomal peptide synthetases as technological platforms for the synthesis of highly modified peptide bioeffectors - Cyclosporin synthetase as a complex example  151

3. Horseradish peroxidase: a valuable tool in biotechnology  199

4. Considerations for the planning and conduct of reproducibility studies of  in vitro diagnostic tests for infectious agents  249

5. Clinical trial methods to discover and validate predictive markers for treatment response in cancer  259

6. Production of high-quality marketing applications: strategies for biotechnology companies working with contract research organizations  269

7. Use of benchmarking in the development of biopharmaceutical products    279

8. The State of biopharmaceutical manufacturing  285

9. review of current authorship guideline and the controversy regarding publication of clinical trial data  303

10. Protein electrostatics: a review of the equations and methods used to model electrostatic equations in biomolecules - Applications in biotechnology  315

11. The development of supportive-care agents for patients with cancer  315