G protein-coupled receptors. Part A / Edited by Arun K. Shukla. -- Cambridge, MA : Academic Press, 2022. – (58.178/P964/v.193)

Contents

Contributors
Preface
1. Computational and experimental approaches to probe GPCR activation and signaling
    1. Introduction
    2. Experimental methods to study GPCR activation and signal transduction
    3. Computational methods to study GPCR activation
    4, Computational methods to study GPCR signal transduction
    5. Viral Hijacking of GPCR Signaling
     References
2. Adrenergic receptors in breast cancer
    1. Breast cancer
    2. Stress
    3. Adrenergic receptors
    4. 132-Adrenergic receptors in the normal breast and breast cancer
    5. Beta-blockers
    6. α2-Adrenergic receptors in breast cancer
    7. Conclusions
    References
3. Tools for adapting to a complex habitat: G-protein coupled receptors in Trichoderma
    1. Introduction
    2. Activation of GPCRs
    3. Downstream targets of GPCR receptors
    4. Regulation mechanisms of GPCRs
    5. GPCRs in Trichoderma
    References
 4. Targeting G protein coupled receptors for alleviating neuropathic pain
     1. Introduction
     2. General etiology of neuropathic pain
     3. Opioid receptors in neuropathic pain
     4. Modulation of mesolimbic circuitry by opioids
     5. Cannabinoid receptors
     6. Chemokines receptors
     7. Adenosine receptors
     8. Conclusion and future prospective
     Acknowledgments
     Conflict of interest
     References
5. Crosstalk between neurons and glia through G-protein coupled receptors: Insights from Caenorhabditis elegans
     1. Introduction
     2. Neuron-glial interactions through neurotransmitter GPCRs
     3. Conclusion
     Acknowledgments
     References
6. Cardiovascular GPCR regulation by regulator of G protein signaling proteins
    1. Introduction
    2. Cardiac GPCRs and RGS proteins
    3. Vascular cardiac GPCRs and RGS proteins
    4, Platelet/other cardiovascular GPCRs and RGS proteins
    5. Conclusions and future perspectives
    References
7. The interaction, mechanism and function of GPR158-RGS7 cross-talk
8. Taste GPCRs and their ligands
    1. Introduction
    2. Currently known ligands
    3. Functional cell-based assays for discovery of taste GPCR ligands
    4. Facilitating ligands discovery through computational methods
    5. Future directions
    6. Concluding remarks
    Acknowledgments
    References
9. Palmitoylation and G-protein coupled receptors
    1. Introduction
    2. S-palmitoylation
    3. Conclusion
    References
Index