Chemical biology of natural products / edited by David J. Newman, Gordon M. Cragg, and Paul G. Grothaus. -- Boca Raton, FL : CRC Press, Taylor & Francis Group, 2017. – (63.35/C517)

Contents

Preface  vii
Editors  xi
Contributors  xv
Chapter 1  Microbial Genome Mining for Natural Product Drug Discovery  1
Chapter 2  Chemical Biology of Marine Cyanobacteria  43
Chapter 3  The Role of Combinatorial Biosynthesis in Natural Products Discovery  87
Chapter 4  Generation of New-to-Nature Natural Products through Synthesis and Biosynthesis: Blending Synthetic Biology with Synthetic Chemistry  127
Chapter 5  Terrestrial Microbial Natural Products Discovery Guided by Symbiotic Interactions and Revealed by Advanced Analytical Methods  161
Chapter 6  Natural Products from Endophytic Microbes: Historical Perspectives, Prospects, and Guidance  189
Chapter 7  Novel Insights in Plant-Endophyte Interactions  205
Chapter 8  Microbial Coculture and OSMAC Approach as Strategies to Induce Cryptic Fungal Biogenetic Gene Clusters  233
Chapter 9  Natural Products of the Rhizosphere and Its Microorganisms: Bioactivities and Implications of Occurrence  285
Chapter 10 Novel Metabolites from Extremophilic Microbes Isolated from Toxic Waste Sites  333
Chapter 11 Deep-Sea Hydrothermal Vent Organisms as Sources of Natural Products  387
Chapter 12 Cone Snail Venom Peptides and Future Biomedical Applications of Natural Products   425
Chapter 13 Naturally Occurring Disulfide-Rich Cyclic Peptides from Plants and Animals: Synthesis and Biosynthesis  491
Chapter 14 Synthesis and Target Identification of Natural Product-Inspired Compound Collections  529
Chapter 15 On the Chemistry and Biology of the Marine Macrolides Zampanolide and Dactylolide  555
Index  601