International review of cell and molecular biology. Volume 374, Mitochondia and bacterial pathogens. Part A / edited by Saverio Marchi, Lorenze Galluzzi. -- Cambridge, MA : Academic Press, c2023. – (58.15/I61/v.374)

Contents

Contributors
1. The bacterial origin of mitochondria: Incorrect phylogenies and the importance of metabolic traits
     1. Introduction
     2. Impact of mass extinction events on the evolution of animals and their mitochondria
     3. Syntrophic models for eukaryogenesis and their metabolic implications
     4. The aerobic ancestry of mitochondria: Systems for cytochrome c biogenesis
     5. Incorrect phylogenies of proteins shared by bacteria and mitochondria
     6. Was the ancestor of mitochondria photosynthetic?
     7. Was the ancestor of mitochondria a facultative or obligate aerobe?
     8. Conclusion
     Acknowledgments
     References
2. Legionella and mitochondria, an intriguing relationship
     1. Introduction
     2. The dynamic contacts between mitochondria and Legionella-containing phagosomes
     3. Regulation of mitochondrial functions by L. pneumophila with metabolic consequences
     4. Regulation of mitochondria during L. pneumophila infection allows to bypass cell-autonomous immunity and to control host cell death
     5. Conclusions
     Acknowledgments
     References
3. Role of mitochondrial outer membrane permeabilization during bacterial infection
     1. Introduction
     2. Mitochondria: Organization and function
     3. Relevance of mitochondria in the context of bacterial infection
     4. Apoptosis and its players
     5. Mitochondrial outer membrane permeabilization (MOMP)
     6. Incomplete MOMP and sub-lethal signals in the mitochondrial apoptosis machine
     7. Modulation of mitochondrial apoptosis by bacterial infection
     8. Induction of MOMP by individual pathogenic bacteria
     9. Induction of sub-lethal signals by infection
     10. Inhibition of MOMP by individual pathogenic bacteria
     11. Concluding remarks
     References
4. The interplay between selective types of (macro)autophagy: Mitophagy and xenophagy
     1. Introduction
     2. Xenophagy and mitophagy act through common molecular mechanisms
     3. Immunity and disease
     4. Conclusions
     Acknowledgments
     Declarations
     References
5. Role of mitochondria in regulating immune response during bacterial infection
     1. Introduction
     2. Mitochondria and metabolism
     3. Mitochondrial dynamics and molecular machineries
     4. Mitochondria mediated immune pathways
     5. Mitochondria mediated cell death and ATP generation
     6. Mitochondria regulating immune functions against specific bacterial infections
     7. Crosstalk between microbiome and mitochondria
     8. Mitochondria centric therapeutics against bacterial infection
     9. Conclusion and future direction
     Acknowledgments
     References