Non-coding rna transcripts in cancer theraphy : pre-clinical and clinical implications / edited by Gautam Sethi, Milad Ashrafizadeh. -- Singapore : World Scientific Publishing Company, 2023. – (64.869/N812)

Contents

Preface
Chapter 1  MicroRNAs (miRNAs) in cancer proliferation: Molecular interactions and possible therapeutic targets
1. Introduction
2. miRNA: Biogenesis and function
3. miRNAs and apoptosis regulation
4. miRNAs and autophagy regulation
5. miRNAs and cell cycle regulation
6. Tumor suppressor miRNAs
7. Tumor-promoting miRNAs
8. Conclusion and remarks
Conflict of interest
References
Chapter 2  MicroRNAs (miRNAs) in cancer metastasis: Molecular interactions and possible therapeutic targets
1. Introduction
2. Role of miRNAs in regulating EMT
3. miRNAs regulating MMPs
4. miRNAs decreasing cancer metastasis
5. miRNAs enhancing cancer metastasis
6. Conclusion and remarks
Conflict of interest
References
Chapter 3  MicroRNAs (miRNAs) in therapy response of human cancers: Biological aspects
1. Introduction
2. Therapies for cancer
3. miRNAs in chemotherapy
4. miRNAs inducing chemo-resistance
5. miRNAs suppressing chemo-resistance
6. miRNAs in radiotherapy
7. miRNAs inducing radio-resistance
8. miRNAs suppressing radio-resistance
9. Conclusion and remarks
Conflict of interest
References
Chapter 4  Exosomal miRNAs in cancer progression and diagnosis
1. Introduction
2. Exosomal miRNAs in cancer progression
3. Exosomal miRNAs and tumor microenvironment
4. Exosomal miRNAs in cancer diagnosis
5. Conclusion and remarks
Conflict of interest
References
Chapter 5  Long non-coding RNAs (lncRNAs) in cancer proliferation: Molecular interactions and possible therapeutic targets
1. Introduction
2. lncRNAs in regulating apoptosis
3. lncRNAs in regulating autophagy
4. lncRNAs in regulating cell cycle progression
5. lncRNAs in regulating glycolysis
6. Onco-suppressor lncRNAs
7. Oncogenic lncRNAs
8. Conclusion and remarks
Conflict of interest
References
Chapter 6  Long non-coding RNAs (lncRNAs) in cancer metastasis: Molecular interactions and possible therapeutic targets
1. Introduction
2. What is the definition of cancer metastasis?
3. lncRNAs in regulating EMT
4. lncRNAs in regulating MMPs
5. lncRNAs in regulating angiogenesis
6. IncRNA/miRNA axis in cancer metastasis
7. Conclusion and remarks
Conflict of interest
References
Chapter 7  Long non-coding RNAs (lncRNAs) in cancer therapy response: Biological aspects
1. Introduction
2. lncRNAs: Overview and role in oncology
3. lncRNAs regulating drug resistance
4. lncRNAs regulating radio-resistance
5. Conclusion and remarks
Conflict of interest
References
Chapter 8  Exosomal long non-coding RNAs (lncRNAs) in cancer progression and diagnosis
1. Introduction
2. Exosomes and their importance in oncology
3. lncRNAs and their Importance in oncology
4. Exosomal lncRNAs in cancer proliferation
5. Exosomal lncRNAs in cancer migration
6. Exosomal lncRNAs in cancer angiogenesis
7. Exosomal lncRNAs in cancer drug resistance
8. Exosomal lncRNAs m cancer radio-resistance
9. Exosomal lncRNAs in cancer diagnosis and prognosis
10. Conclusion and remarks
Conflict of interest
Acknowledgment
Funding
References
Chapter 9  Circular RNAs (circRNAs) in cancer proliferation: Molecular interactions and possible therapeutic targets
1. Introduction
2. circRNAs in apoptosis regulation
3. circRNAs in autophagy regulation
4. circRNAs in cancer cell glycolysis
5. circRNAs with oncogenic function
6. circRNAs with onco-suppressor function
7. Conclusion and remarks
Conflict of interest
References
Chapter 10 Circular RNAs (circRNAs) in cancer metastasis: Molecular interactions and possible therapeutic targets
1. Introduction
2. An overview of cancer metastasis and related pathways
3. circRNAs in EMT regulation
4. circRNAs in MMP regulation
5. circRNAs in angiogenesis regulation
6. circRNA/miRNA axis in regulating cancer metastasis
7. Conclusion and remarks
Conflict of interest
References
Chapter 11 Circular RNAs (CircRNAs) in cancer therapy response: Biological aspects
1. Introduction
2. Cancer therapy resistance
3. An introduction to the role of circRNAs in oncology
4. circRNAs in cancer drug resistance
5. circRNAs in cancer radio-resistance
6. Conclusion and remarks
Conflict of interest
References
Chapter 12 Exosomal circular RNAs (circRNAs) in cancer progression and diagnosis
1. Introduction
2. Exosomes as extracellular vesicles: Basics and biogenesis
3. Exosomes: Basics in cancer
4. Exosomal circRNAs in cancer proliferation
5. Exosomal circRNAs in cancer metastasis
6. Exosomal circRNAs and related molecular pathways
7. Exosomal circRNAs and drug resistance
8. Exosomal circRNAs and radio-resistance
9. Exosomal circRNAs as biomarkers in cancer
10. Conclusion and remarks
Conflict of interest
References
Index