Cell death : apoptosis and other means to an end / Douglas R. Green. -- 2nd edition. -- Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, 2018. – (58.1575 /G795 /2nd ed.)

Contents

Foreword from the First Edition by Martin Raft, ix

Preface from the First Edition, xi

Foreword by Shigekazu Nagata, xiii

Preface, xv

Introduction, xvii

1  A Matter of Life and Death, I

2  Caspases and Their Substrates, 11

3  Caspase Activation and Inhibition, 27

4  The Mitochondrial Pathway of Apoptosis, Part I: MOMP and Beyond, 45

5  The Mitochondrial Pathway of Apoptosis, Part II: the BCL-2 Protein Family, 61

6  The Death Receptor Pathway of Apoptosis, 89

7  Inflammasomes and Other Caspase-Activation Platforms, 103

8  Nonapoptotic Cell Death Pathways, 121

9  The Burial: Clearance and Consequences, 149

10  Cell Death in Development, 179

11  Cell Death and Cancer, 195

12  The Future of Death, 217

Figure Credits, 233

Additional Reading, 237

Index, 263