Mass spectrometry of nucleosides and nucleic acids / edited by Joseph H. Banoub, Patrick A. Limbach. -- Boca Raton : CRC Press, c2010. – (58.174257 /M414)

Contents

Preface

Editors

Contributors

Chapter 1  Overview of Recent Developments in the Mass Spectrometry of Nucleic Acid and Constituents

Chapter 2  Mass Spectrometric Analysis of Deoxyinosines

Chapter 3  Tandem Mass Spectrometry of Nucleic Acids

Chapter 4  Mass Spectrometric Application in the Study of Cyclic Nucleotides in Biochemical Signal Transduction

Chapter 5  Analysis of Urinary Modified Nucleosides by Mass Spectrometry

Chapter 6  Mass Spectrometric Determination of DNA Adducts in Human Carcinogenesis

Chapter 7  Sequence Distribution of Nucleobase Adducts Studied by Isotope Labeling of DNA-Mass Spectrometry

Chapter 8  Electrospray Mass Spectrometry of Noncovalent Complexes between Small Molecule Ligands and Nucleic Acids

Chapter 9  Electrospray Ionization-Mass Spectrometry for the Investigation of Protein-Nucleic Acid Interactions

Chapter 10  Characterization of Noncovalent Complexes of Nucleic Acids with Peptides and Proteins by Mass Spectrometry

Chapter 11  MALDI-TOF Detection of Specific Noncovalent Complexes of Highly Acidic Biomolecules with Pyrenemethylguanidinium

Chapter 12  Quantitative Identification of Nucleic Acids via Signature Digestion Products Detected Using Mass Spectrometry

Chapter 13  Electrospray Ionization Mass Spectrometry for the Direct Analysis of Modified Nucleosides in Small RNAs

Chapter 14  LC-MS/MS for the Examination of the Cytotoxic and Mutagenic Properties of DNA Lesions In Vitro and In Vivo

Chapter 15  Influence of Metal Ions on the Structure and Reactivity of Nucleic Acids

Index