RNA editing : methods and protocols / edited by Ernesto Picardi and Graziano Pesole. -- New York, NY : Humana Press, 2021. – (58.17 /M592 /v.2181)

Contents

Dedication

Foreword

Preface

Contributors

1  Substitutional RNA Editing in Plant Organelles

2  Computational Detection of Plant RNA Editing Events

3  Discovering RNA Editing Events in Fungi

4  C-to-U RNA Editing: From Computational Detection to Experimental Validation

5  Live-Cell Quantification of APOBEC1-Mediated RNA Editing: A Comparison of RNA Editing Assays

6  Adenosine-to-Inosine RNA Editing Enzyme ADAR and microRNAs.

7  Quantitative Analysis of Adenosine-to-Inosine RNA Editing

8  Discovering A-to-I RNA Editing Through Chemical Methodology "ICE-seq"

9  ALU A-to-I RNA Editing: Millions of Sites and Many Open Questions

10  RNA Editing in Human and Mouse Tissues

11  Bioinformatics Resources for RNA Editing

12  High-Throughput Sequencing to Detect DNA-RNA Changes

13  Detection of A-to-I Hyper-edited RNA Sequences

14  Proteome Diversification by RNA Editing

15  MicroRNA Editing Detection and Function: A Combined In Silico and Experimental Approach for the Identification and Validation of Putative Oncogenic Targets

16  RNA Editing in Interferonopathies

17  The Role of RNA Editing in the Immune Response

18  RNA Editing in Neurological and Neurodegenerative Disorders

19  New Frontiers for Site-Directed RNA Editing: Harnessing Endogenous ADARs

Index