Cancer preventive and therapeutic compounds : gift from mother nature / edited by Sahdco Prasad & Amit Kumar Tyagi. -- Sharjah : Bentham Science Publishers, 2017. – (64.863/C215)

Contents

FOREWORD

PREFACE

LIST OF CONTRIBUTORS

CHAPTER 1  DIETARY AGENTS: EFFECTIVE AND SAFE NATURAL ASSETS AGAINST CANCER  3

      INTRODUCTION  3

      FRUITS AND VEGETABLES  5

      LEGUMES  8

      GRAINS AND CEREALS  9

      NUTS  11

      SPICES  12

      CONCLUSION  13

      CONFLICT OF INTEREST  14

      ACKNOWLEDGEMENTS  14

      REFERENCES-  14

CHAPTER 2  MEDICINAL IMPORTANCE OF ALLICIN - A BIOACTIVE COMPONENT FROM ALLIUM SATIVUM L (GARLIC)  20

      INTRODUCTION  20

      CONCLUDING REMARKS  26

      CONFLICT OF INTEREST  26

      ACKNOWLEDGEMENTS  26

      REFERENCES  27

CHAPTER 3  BOSWELLIC ACIDS AS POTENTIAL CANCER THERAPEUTICS  32

      INTRODUCTION  32

     CONCLUSION  54

      CONFLICT OF INTEREST  54

      ACKNOWLEDGEMENTS  54

      REFERENCES  54

CHAPTER 4  NATURAL COMPOUNDS: CANCER PREVENTIVE AGENTS  64

     INTRODUCTION  64

      CANCER PREVENTION THROUGH NATURAL SOURCES  65

     MOLECULAR TARGETS FOR NATURAL CHEMOPREVENTIVE AGENTS  76

     CONCLUDING REMARKS  80

      CONFLICT OF INTEREST  82

      ACKNOWLEDGEMENTS  82

      REFERENCES  82

CHAPTER 5  AFRICAN MEDICINAL PLANTS: AN UNTAPPED RESERVOIR OF POTENTIAL ANTICANCER AGENTS  87

     INTRODUCTION  87

      SOME ISOLATED COMPOUNDS FROM AFRICAN MEDICINAL PLANTS WITH MEASURED ANTICANCER ACTIVITY  89

      CONCLUSION

      CONFLICT OF INTEREST  99

      ACKNOWLEDGEMENTS    99

      REFERENCES  99

CHAPTER 6  PHYTOCHEMICALS IN THERAPY OF RADIATION INDUCED DAMAGE AND CANCER

      INTRODUCTION  105

     CONCLUSION  116

      CONFLICT OF INTEREST  116

      ACKNOWLEDGEMENT  116

      REFERENCES  117

CHAPTER 7  MARINE NATURAL PRODUCTS FOR CANCER PREVENTION AND THERAPY: A MECHANISTIC OVERVIEW    125

      INTRODUCTION  125

     CONFLICT OF INTEREST  140

      ACKNOWLEDGEMENTS  140

      REFERENCES  140

CHAPTER 8  NATURAL PRODUCTS AS A UNIQUE SOURCE OF ANTI-CANCER AGENTS  147

      INTRODUCTION  147

      TREATMENT MODALITIES OF CANCER  148

      HISTORY OF NATURAL COMPOUNDS AS CANCER THERAPEUTICS  150

      ROLE OF MARINE NATURAL COMPOUNDS AND THEIR DERIVATIVES IN CANCER PREVENTION

     CONCLUSION  167

      CONFLICT OF INTEREST  168

      ACKNOWLEDGEMENTS  168

      REFERENCES  168

CHAPTER 9  TRANSLATION OF NATURAL PRODUCTS INTO CLINICALLY EFFECTIVE DRUGS: HOW FAR WE HAVE GONE  182

      INTRODUCTION  183

      PROSTATE CANCER  183

      COLORECTAL CANCER  185

      LUNG CANCER  185

      HEPATOCELLULAR CARCINOMA  186

      PANCREATIC CANCER  186

      NATURAL PRODUCT INDUCED MODULATION OF EPIGENETIC MACHINERY  187

      CONCLUSION  189

      CONFLICT OF INTEREST  190

      ACKNOWLEDGEMENTS  190

      REFERENCES  190

SUBJECT INDEX  194