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DNA recombination : a subject collection from Cold Spring Harbor perspectives in biology / edited by Stephen Kowalczykowski, Neil Hunter, Wolf-Dietrich Heyer. -- Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, c2016. – (58.1481/D629) |
Contents
Preface
PART 1: MECHANISMS OF RECOMBINATION
An Overview of the Molecular Mechanisms of
Recombinational DNA Repair, 1
Sources of DNA Double-Strand Breaks and Models of
Recombinational DNA Repair, 37
End Resection at Double-Strand Breaks: Mechanism
and Regulation, 55
DNA-Pairing and Annealing Processes in Homologous
Recombination and Homology-Directed Repair, 73
Mediators of Homologous DNA Pairing, 93
Regulation of DNA Pairing in Homologous
Recombination, 109
The Dissolution of Double Holliday Junctions, 125
Holliday Junction Resolvases, 139
Structural Studies of DNA End Detection and
Resection in Homologous Recombination, 169
PART 2: REGULATION OF RECOMBINATION AND GENOMIC
MAINTENANCE
Regulation of Recombination and Genomic
Maintenance, 195
Cell Biology of Mitotic Recombination, 217
Transcription and Recombination: When RNA Meets
DNA, 239
Recombination and Replication, 255
Mismatch Repair during Homologous and Homeologous
Recombination, 269
The Role of Double-Strand Break Repair Pathways at
Functional and Dysfunctional Telomeres, 291
Mechanisms of Gene Duplication and Amplification,
307
Homologous Recombination and Human Health: The
Roles of BRCA1, BRCA2, and Associated
Proteins, 333
PART 3: MEIOTIC RECOMBINATION
Meiotic Recombination: The Essence of Heredity, 361
Recombination, Pairing, and Synapsis of Homologs
during Meiosis, 397
Mechanism and Regulation of Meiotic Recombination
Initiation, 423
Initiation of Meiotic Homologous Recombination:
Flexibility, Impact of Histone Modifications, and Chromatin Remodeling, 447
DNA Strand Exchange and RecA Homologs in Meiosis,
463
The Meiotic Checkpoint Network: Step-by-Step
through Meiotic Prophase, 493
Meiosis and Maternal Aging: Insights from Aneuploid
Oocytes and Trisomy Births, 519
Index, 539
