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Cancer stem cells / edited by Vinagolu K. Rajasekhar. -- Hoboken, New Jersey : Wiley Blackwell, c2014. – (64.8/C215c) |
Contents
Contents
About the Editor
Contributors
Foreword
Preface
Acknowledgments
Section I Essentials of Cancer Stem Cells and Conceptual Modeling
1 Theoretical and Experimental Foundations of the "Cancer Stem Cell" Model
2 The Hallmarks of Prostate Cancer Stem Cells
3 Self-Renewal， Induced Proliferation， and Autonomous Cell Growth Represent Distinct Modes of Cell Multiplication: Relevance to the Cancer Stem Cell Theory
4 Human Embryonic Stem Cells and Cancer: Modeling Disease in a Dish
5 Cancer Stem Cell as a Result of a Reprogramming-Like Mechanism: Implications in Tumor Development and Treatment
6 A Cancer Stem Cell Model: An Insight into the Conversion of Induced Pluripotent Stem Cells to Cancer Stem-Like Cells
7 Altruistic Stem Cells and Cancer Stem Cells
8 The Emerging Concept of EMT-Induced Cancer Stem Cells
9 Models to Study Chronic Myeloid Leukemia Cancer Stem Cells
10 Cancer Stem Cells in Melanoma: Biomarkers and Mathematical Models
Section II Stem Cells in Liquid Tumors
11 Acute Myeloid Leukemia Stem Cells--Updates and Controversies
12 Leukemia-Initiating Cells in Acute Lymphoblastic Leukemia
Section III Stem Cells in Solid Tumors
13 Lung Cancer Stem Cells and Resistance to Radiotherapy
14 Prostate Cancer Cell Heterogeneity and Prostate Cancer Stem Cells
15 Glioblastoma Stem Cells Drive Tumor Recurrence and Patient Relapse: What's the Evidence?
16 Stem Cells and Pancreatic Cancer
17 Melanoma Subpopulations with Cancer Stem Cell Phenotypes
18 Sarcoma Stem Cells
Section IV Cancer Stem Cells in Tumor Metastasis Perspective
19 Cancer Stem Cells in Metastasis and Minimal Residual Disease
20 Role of Cancer Stem Cells in Metastasis
21 Cancer Stem Cells and the Stromal Microenvironment
22 A Perspective on Breast Cancer Malignant Progression: From Cancer Stem Cell Intra Tumor Heterogeneity to Metastasis-Initiating Cells
Section V Novel and Potential Targets in Cancer Stem Cells
23 Targeting Cancer Stem Cells--Modulating Embryonic Stem Cell Signaling， Epigenetics， and Tumor Metabolism
24 Oct4， Oct1， and Cancer Stem Cells
25 The Role of Cripto-1 in Cancer and Cancer Stem Cells
26 Leptin Signaling in the Regulation of Stem and Cancer Stem Cells
27 Tumor-Initiating Stem-Like Cells: Carcinogenesis through Toll-Like Receptors， Environmental Factors， and Virus
28 The Role of Epithelial Cell Polarity Pathways on Cancer Stem Cells
29 Cancer-Initiating Cells， Exosomes， and the Premetastatic Niche
30 MicroRNA Therapeutics to Target Brain Tumor Stem Cells
31 The Riboproteome Orchestrates Self-Renewal and Cell Fate in Leukemia
Section VI Clinical Relevance of Cancer Stem Cells in Patients
32 Targeting Different States of Breast Cancer Stem Cells
33 Difficulties in Targeting the Beating Heart: Therapeutic Implications
of the Cancer Stem Cell Hypothesis in Melanoma
34 Targeting Cancer Stem Cells for Overcoming Drug Resistance and Cancer Progression
35 The Role of Cancer Stem Cells in Tumor Radioresistance
Index
Color plate located between pages 2 72 and 2 73
