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Computational neuroscience : simulated demyelinating neuropathies and neuronopathies / Diana Ivanova Stephanova, Bozhidar Dimitrov. -- Boca Raton : CRC Press, c2013. – (59.429 /S827)

Contents

    CONTENTS
    
    NERVE FIBRES: Myelinated Axons
    Demyelinating Neuropathies
    Neuronopathies
    Axonal Excitability
    Mathematical Modeling of the Nerve Fibres
    MODELS AND METHODS FOR INVESTIGATION OF THE HUMAN MOTOR NERVE FIBRE: Multi-Layered and Double Cable Models
    Line-Source Model
    Methods of Stimulation and Calculation of the Potentials
    Methods for Calculation of the Strength-Duration Time
    Constants, Rheobasic Currents and Recovery Cycles
    SIMULATED DEMYELINATING NEUROPATHIES AND NEURONOPATHIES: Simulation of CMT1A, CIDP, Subtypes CIDP, GBS, MMN, and ALS
    Abnormalities in the Potentials Action Potentials
    Electrotonic Potentials
    Abnormalities in the Extracellular Potentials and their Mechanisms
    Abnormalities in the Strength-Duration Time Constants, Rheobasic Currents and Their Mechanisms
    Abnormalities in the Recovery Cycles and Their Mechanisms
    EFFECT OF THE MYELIN SHEATH AQUEOUS LAYERS ON THE EXCITABILITY PROPERTIES OF THE SIMULATED HEREDITARY AND CHRONIC DEMYELINATING NEUROPATHIES: Simulation of the CMT1A, CIDP and Subtypes CIDP with Aqueous Layers within the Myelin Sheath
    Effect of the Myelin Sheath Aqueous Layers on the Potentials
    Effect of the Myelin Sheath Aqueous Layers on the Strength-Duration Time Constants, Rheobasic Currents and Recovery Cycles
    References