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Resident stem cells and regenerative therapy / edited by Regina Coeli dos Santos Goldenberg, Antonio Carlos Campos de Carvalho. — Oxford ;Waltham , MA : Academic Press, 2013. – (61.268/R433) |
Contents
Contents
Foreword
List of Contributors
1 Resident Stem Cells in Kidney Tissue
Introductory Remarks
Brief Description of the Structural Organization of the Mammalian Adult Kidney
Stem Cells in Kidney Organogenesis
Kidney Stem/Progenitor Cells: Niches and Isolation
The Role of Stem/Progenitor Cells in Kidney Regeneration
Role of Kidney Resident Stem/Progenitor Cells in the Establishment and Progression of Renal Disorders
Glomerularsclerosis
Tubular Lesions
Progenitor/Resident Stem Cells and Renal Cancer
Stem/Progenitor Cells in Kidney: Features for Therapeutic Use after the Few Trials with Bone Marrow Cells?
References
2 Pancreatic Stem Cells
Introduction
Embryogenesis and Organogenesis
References
3 Tissue Engineering and the Role of Biomaterial
Introduction to Tissue Engineering
Role of Biomaterials in Tissue Engineering
Clinical Translation and Commercialization
Future of Tissue Engineering
Cardiac Tissue Engineering
Future of Cardiac Tissue Engineering
References
4 Resident Neural Stem Cells
Neurogenesis in the Adult Brain
Neurogenesis during Development
Neural Stem Cells
The Subventricular Zone
Subgranular Zone
Neural Stem Cell Markers
Neurogenesis's Regulators
Cell Therapy
References
5 Resident Stem Cell in Skin
Introduction
Interfollicular Epidermis
Hair Follicle and Associated Structures
Melanocytes
Dermis
Cell Therapies and Clinical Application of Skin Stem Cells
References
6 Lung Resident Stem Cells
Lung Structure
Hierarchy of Lung Resident Stem Cells
Resident Epithelial Progenitor Cells
Resident Endothelium Progenitor Cells
Resident Mesenchymal Progenitor Cells
Lung Resident Stem Cells in Respiratory Diseases
Main Challenges for the Identification of Lung Resident Stem Cells
References
7 Skeletal Resident Stem Cells
Bone Tissue
Bone Marrow as a Source of Mesenchymal Stem
Cells-Stem Cells for Bones
Mesenchymal Cells in Orthopedic Bioengineering and Bone Repair
Skeletal Stem Cells and the Vascular System
Combined Action: Therapeutic Use of Mesenchymal Progenitors and Angiogenic Progenitors
Cell Therapy in Pseudarthrosis
Cell Therapy in Avascular Necrosis of the Femoral Head (Osteonecrosis)
Acknowledgments
References
8 Cardiac Stem Cells
c-Kit Positive Cells
Cardiosphere-Derived Cells
Side Population
Islet-1 Positive Cells
Conclusions and Future Directions
References
9 The Neural Crest and the Stem Cells of Neural Crest
Introduction
The Neural Crest
Neural Crest-Derived Stem Cells (NCSCs)
Are NC Cells a Source of Mesenchymal Stem Cells (MSCs)?
Concluding Remarks
Acknowledgments
References
10 Liver Resident Stem Cell
Introduction
Liver Development
Liver Regeneration: The Hierarchy for Cell Response
Stem/Progenitor Cells: The Second Front in Liver Regeneration
Fetal Hepatic Stem Cell Niche
Adult Liver Stem/Progenitor Cell Niche
Liver Stern/Progenitors Cells and Cell Therapy
References
11 Telocytes and Stem Cells
What Are Telocytes?
What Defines Telocytes as a Unique， Distinct Cell Type?
Comparison with Fibroblasts
Where Are Telocytes Located?
Telocyte Intercellular Relationships
Phenotype "Portrait"
The Tandem Telocytes & Stem Cells
A Hope for Regenerative Medicine
Future Research Directions
References
12 Pericytes as the Source of Mesenchymal Stem Cells
Pericytes
Relationship between Pericytes and MSCs
The Plasticity Issue
Pericytes as Stem Cells in the Body
Conclusion
Acknowledgments
References
