Small molecule microarrays : methods and protocols / edited by Mahesh Uttamchandani, Shao Q. Yao. — New York, N.Y. : Humana, c2010. – (58.17/M592/v.669)

Contents

    Contents
    
    Preface
    Contributors
    1. The Expanding World of Small Molecule Microarrays
    2. Construction of Photo-Cross-Linked Microarrays of Small Molecules
    3. Small Molecule Microarray: Functional-Group Specific Immobilization of Small Molecules
    4. Detecting Protein-Small Molecule Interactions Using Fluorous Small Molecule Microarrays
    5. A Method for Small Molecule Microarray-Based Screening for the Rapid Discovery of affinity-Based Probes
    6. Nanodroplet Chemical Microarrays and Label-Free Assays
    7. Nanodroplet Microarrays for High-Throughput Enzyme Screening
    8. The Application of the Chemical Array for Biological Study
    9. Peptide Arrays with a Chip
    10. In situ Chemical Modification of Peptide Microarrays: Characterization by Desorption/Ionization on Silicon Nanowires 125
    11. In situ Chemical Modification of Peptide Microarrays: Application to the Study of the Antibody Responses to Methylated Antigens
    12. Peptide Microarrays on Coated Silicon Slides for Highly Sensitive Antibody Detection
    13. Antibody Signatures Defined by High-Content Peptide Microarray Analysis
    14. High Density Peptide Microarrays for Proteome-Wide Fingerprinting of Kinase Activities in Cell Lysates 173
    15. A Peptide Microarray for Detecting Protein Kinase Activity in Cell Lysates 183
    16. Chemical Microarrays Constructed by Selective Attachment of Hydrazide-Conjugated Substances to Epoxide Surfaces and Their Applications
    17. A Microarray-Based Method to Perform Nucleic Acid Selections
    Index