Systems biology in drug discovery and development : methods and protocols / edited by Qing Yan. — New York, NY : Humana Press, 2010. – (58.17/M592/v.662)

Contents

    CONTENTS
    
    Preface
    Contributors
    PART I METHODOLOGIES OF SYSTEMS BIOLOGY IN DRUG DISCOVERY AND DEVELOPMENT
    1 Proteomics and Systems Biology: Application in Drug Discovery and Development
    2 Systems Biology Approaches and Tools for Analysis of Interactomes and Multi-target Drugs
    3 Systems Biology "On-the-Fly": SILAC-Based Quantitative Proteomics and RNAi Approach in Drosophila melanogaster
    4 Systems Biology of Cell Behavior
    5 Computational Modeling in Systems Biology
    6 An Introduction to Gaussian Bayesian Networks
    7 Derivation of Large-Scale Cellular Regulatory Networks from Biological Time Series Data
    8 Translational Bioinformatics and Systems Biology Approaches for Personalized Medicine
    PART II SYSTEMS BIOLOGY METHODS FOR DISEASE TREATMENT AND TRANSLATIONAL MEDICINE
    9 Systems Biology and Inflammation
    10 Immunoinformatics and Systems Biology Methods for Personalized Medicine
    11 Systems Biology Approaches to the Study of Cardiovascular Drugs
    12 Cancer Systems Biology
    13 Systemic Lupus Erythematosus: From Genes to Organ Damage
    14 Systems Biology of Influenza: Understanding Multidimensional Interactions for Personalized Prevention and Treatment
    15 Methods in Systems Biology of Experimental Methamphetamine Drug Abuse
    16 Systems Biology and Theranostic Approach to Drug Discovery and Development to Treat Traumatic Brain Injury
    Index