Cancer systems biology / editor by Edwin Wang. — Boca Raton, Fla. : CRC ; London : Taylor & Francis [distributor], 2010. – (64.8/C215s)

Contents

    Contents
    
    Foreword， xi
    Preface， xiii
    About the Editor， xv
    Contributors， xvii
    SECTION I Cancer Systems Biology: Concepts and Applications
    CHAPTER 1 A Roadmap of Cancer Systems Biology
    CHAPTER 2 Network Biology， the Framework of Systems Biology 23
    CHAPTER 3 Reconstructing Gene networks using gene expression profiles
    CHAPTER 4 Understanding Cancer Progression in Protein Interaction Networks
    CHAPTER 5 From tumor genome sequencing to cancer signaling maps
    CHAPTER 6 Ubiquitin-Mediated Regulation of Human Signal Networks in Normal and Cancer Cells
    CHAPTER 7 microRNA Regulation of Networks of Norma and Cancer Cells
    CHAPTER 8 Network model of survival signaling in T-cell large granular lymphocyte leukemia
    CHAPTER 9 Cancer metabolic networks: metabolic pathways modeling and metabolomics in cancer research
    CHAPTER 10 Warburg Revisited: Modeling Energy Metabolism for Cancer Systems Biology
    CHAPTER 11 Cancer Gene Prediction Using a Network Approach 191
    SECTION II Cancer Biology: Basic Concepts and Cutting-Edge Topics
    CHAPTER 12 Cancer Genomics to Cancer Biology
    CHAPTER 13 Epithelial-to-mesenchymal transition (EMT): The good， the bad， and the ugly
    CHAPTER 14 Tumors and Their Microenvironments
    CHAPTER 15 Tumor Angiogenesis: Cell-Microenvironment Interactions 283
    SECTION III Data Resources and Software Tools for Cancer Systems Biology
    CHAPTER 16 Modeling Tools for Cancer Systems Biology
    CHAPTER 17 Advanced Visualization， Analysis， and Inference of Biological Networks Using VisANT
    CHAPTER 18 Gene Set and Pathway-Based Analysis for Cancer Omics 351
    CHAPTER 19 SH2 Domain Signaling Network and Cancer
    CHAPTER 20 Data Sources and Computational Tools for Cancer Systems Biology
    INDEX， 395