Vaccine adjuvants : methods and protocols / edited by Gwyn Davies. — New York : Humana, 2010. – (58.17/M592/v.626)

Contents

    Contents
    
    Preface
    Contributors
    1. Immunology of Vaccine Adjuvants
    2. Preclinical Development of AS04
    3. Nonclinical Safety Assessment of Vaccines and Adjuvants 29
    4. Aluminum Adjuvants: Preparation， Application， Dosage， and Formulation with Antigen 41
    5. Freund's Complete and Incomplete Adjuvants， Preparation， and Quality Control Standards for Experimental Laboratory Animals Use 59
    6. Liposomal Adjuvants: Preparation and Formulation with Antigens 73
    7. Micro/Nanoparticle Adjuvants: Preparation and Formulation with Antigens
    8. Adjuvant Activity on Human Cells In Vitro
    9. Adjuvant Activity on Murine and Human Macrophages
    10. In Vitro Effects of Adjuvants on B Cells
    11. NKT Cell Responses to Glycolipid Activation 149
    12. Tracking Dendritic Cells In Vivo
    13. Adjuvant Effects on Antibody Titre
    14. Functional Antibody Assays
    15. Determining Adjuvant activity on T-cell Function In vivo: Th Cells
    16. Quantitative Multiparameter Assays to Measure the Effect of Adjuvants on Human Antigen-Specific CD8 T-cell Responses 231
    17. Large-Animal Model for Establishing E/T Ratio of Adjuvants
    18. Determining the Activity of Mucosal Adjuvants
    19. Adjuvant Activity of Cytokines