Bioinformatics and functional genomics / by Jonathan Pevsner. — 2nd ed. — Hoboken, N.J. : Wiley-Blackwell, c2009. – (58.1423/P514/2nd ed.) |
Contents
Contents
PART l ANALYZING INA, BNA, ANI PBOTEIN SEQUENCES IN IATABASES
1 Introduction, 3
2 Access to Sequence Data and Literature Information, 13
3 Pairwise Sequence Alignment, 47
4 Basic Local Alignment Search Tool (BLAST), 101
5 Advanced Database Searching, 141
6 Multiple Sequence Alignment, 179
7 Molecular Phylogeny and Evolution, 215
PART II GENOMEWIDE ANALYSIS OF BNA AND PROTEIN
8 Bioinformatic Approaches to Ribonucleic Acid (RNA), 279
9 Gene Expression: Microarray Data Analysis, 331
10 Protein Analysis and Proteomics, 379
11 Protein Structure, 421
12 Functional Genomics, 461
PART III GENOME ANALYSS
13 Completed Genomes, 517
14 Completed Genomes: Viruses, 567
15 Completed Genomes: Bacteria and Archaea, 597
16 The Eukaryotic Chromosome, 639
17 Eukaryotic Genomes: Fungi, 697
18 Eukaryotic Genomes: From Parasites to Primates, 729
19 Human Genome, 791
20 Human Disease, 839
Glossary, 891
Answers to Self-Test Quizzes, 909
Author Index, 911
Subject Index, 913