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Nanostructure design : methods and protocols / edited by Ehud Gazit, Ruth Nussinov. — Totowa, N.J. : Humana Press, c2008. – (58.17/M592/v.474) |
Contents
Contents
Preface
Contributors
PART I EXPERIMENTAL APPROACH
1 Molecular Design of Performance Proteins With Repetitive Sequences: Recombinant Flagelliform Spider Silk as Basis for Biomaterials 3
2 Creation of Hybrid Nanorods of Natural Trimeric Fibrous From Sequences Proteins Using the Fibritin Trimerization Motif 15
3 The Leucine Zipper as a Building Block for Self-Assembled Protein Fibers 35
4 Biomimetic Synthesis of Bimorphic Nanostructures 53
5 Synthesis and Primary Characterization of Self-Assembled Peptide-Based Hydrogels
6 Periodic Assembly of Nanospecies on Repetitive DNA Sequences Generated on Gold Nanoparticles by Rolling Circle Amplification
PART II COMPUTATIONAL APPROACH
7 Protocols for the In Silico Design of RNA Nanostructures 93
8 Self-Assembly of Fused Homo-OI
9 Computational Methods in Nanostructure Design: Replica Exchange Simulations of Self-Assembling Peptides 133
10 Modeling Amyloid Fibril Formation: A Free-Energy Approach 153
11 Computer Modeling in Biotechnology: A Partner in Development 181
12 What Can We Learn From Highly Connected β-Rich Structures for Structural Interface Design? 235