Current topics in developmental biology. v. 79 / edited by Gerald P. Schatten. — Amsterdam : Elsevier, c2007. – (58.12/C976/v.79)

Contents

    Contents
    
    Contributors ix
    1 The Development of Synovial Joints
    I. Introduction 2
    II. Specification and Patterning of the Joint 5
    III. Joint Cavitation and the Role of Mechanical Stimuli 13
    IV. Cell Matrix Interactions During Joint Formation 19
    V. The Development of Articular Cartilage: Overview 22
    VI. Aspects of Postnatal Joint Biology 23
    References 28
    2 Development of a Sexually Differentiated Behavior and Its Underlying CNS Arousal Functions
    I. Introduction 38
    II. Sexual Differentiation of Brain Mechanisms Producing Lordosis Behavior 41
    III. Development of Brain Mechanisms Underlying Arousal 53
    IV. Outlook for New Work on Sexually Differentiated Behaviors 54
    References 56
    3 Phosphodiesterases Regulate Airway Smooth Muscle Function in Health and Disease
    I. Introduction 61
    II. Developmental and Physiological Responses Regulated by PDEs 65
    III. PDEs and Airway Smooth Muscle Function 67
    IV. Cytokine and Chemokine Secretion by ASM: A Role for PDEs 69
    V. Conclusions 70
    Acknowledgments 70
    References 71
    4 Role of Astrocytes in Matching Blood Flow to Neuronal Activity
    I. Introduction 76
    II. Neurovascular Unit 76
    III. Neuron Astrocyte Interactions and Regulation of Synaptic Transmission in the Brain 78
    IV. Neurovascular Coupling: Role of Astrocytes 82
    V. Summary 89
    References 90
    5 Elastin-Elastases and Inflamm-Aging
    I. Introduction
    II. Elastic Fibers: Formation and Degradation 103
    III. Biological Activities of Elastin Peptides (EPs): The "Elastin Receptor System"
    IV. Elastolysis， Aging， and AAAs 117
    V. The Elastin Connection in Melanoma 127
    VI. Concluding Remarks 135
    References 138
    6 A Phylogenetic Approach to Mapping Cell Fate
    I. Development 158
    II. Fate Maps 159
    III. Limited Information from Cell Marking 165
    IV. Stochastic Nature of Development in Higher Organisms 168
    V. A New Approach: Phylogenetic Fate Mapping 171
    VI. Challenges Dealing with Randomness in Development 177
    VII. Extended Applications of Phylogenetic Fate Mapping 179
    Acknowledgments 180
    References 180
    Index 185
    Contents of Previous Volumes 191