The molecular biology of cancer / edited by Stella Pelengaris and Michael Khan. — Malden, MA ; Oxford : Blackwell Pub., 2006. – (64.83/M718)

Contents

    Contents
    
    Contributors vi
    Preface viii
    Acknowledgments
    1 Introduction 1
    2 The Burden of Cancer 35
    3 Nature and Nurture in Oncogenesis 61
    4 DNA Replication and the Cell Cycle 88
    5 Regulation of Growth: Growth Factors， Receptors， and Signaling Pathways 120
    6 Oncogenes 158
    7 Tumor Suppressor Genes 219
    8 Apoptosis 251
    9 Telomeres and Senescence 279
    10 Genetic Instability， Chromosomes， and Repair 296
    11 Cancer is More Than a Genetic Condition 326
    12 Cell-Matrix Adhesion， Cell-Cell Interactions， and Malignancy 357
    13 Tumor Immunity and Immunotherapy 389
    14 Angiogenesis 411
    15 Diagnosis of Cancer 424
    16 Treatment of Cancer: Chemotherapy and Radiotherapy 444
    17 Caring for the Cancer Patient 464
    18 Genomics and Proteomics in Cancer Research and Diagnosis 478
    Glossary 508
    Answers to Questions 514
    Index 518