Cold Spring Harbor Symposium on Quantitative Biology. v. 71, Regulatory RNAs / meeting organized by Bruce Stillman and David Stewart. — Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press, c2006.—(58/C688/v.71)

Contents

        Contents
    
    Introduction
    Small RNA Regulators and the Bacterial Response to Stress
    Short Silencing RNA: The Dark Matter of Genetics?
    Misexpression of the Caenorhabditis elegans miRNA let-7 Is Sufficient to Drive Developmental Programs
    Function and Localization of MicroRNAs in Mammalian Cells
    
    Mechanism and Biology of RNAi
    The RNAi Pathway Initiated by Dicer-2 in Drosophila
    Molecular Mechanism of Target RNA Transcript Recognition by Argonaute-Guide Complexes
    Drosha in Primary MicroRNA Processing
    Substrate Selectivity of Exportin 5 and Dicer in the Biogenesis of MicroRNAs
    The Argonautes
    Structure of Dicer and Mechanistic Implications for RNAi
    Structural Biology of RNA Silencing and Its Functional implications
    Systemic RNAi in Caenorhabditis elegans
    
    Genome-wide Approaches
    Transcriptional Landscape of the Human and Fly Genomes: Nonlinear and Multifunctional Modular Model of Transcriptomes
    Novel Transcribed Regions in the Human Genome
    Computational Analysis of RNAs
    MicroRNAs in Search of a Target
    RNomics: Identification and Function of Small Non-Protein-coding RNAs in Model Organisms
    Drosophila Genome-wide RNAi Screens: Are They Delivering the Promise?
    Deep Conservation of MicroRNA-target Relationships and 3'UTR Motifs in Vertebrates， Flies， and Nematodes
    
    Small RNAs in Development
    Organ Polarity in Plants Is Specified through the Opposing Activity of Two Distinct Small Regulatory RNAs
    The Function of RNAi in Plant Development
    rasiRNAs， DNA Damage， and Embryonic Axis Specification
    Architecture of a MicroRNA-controlled Gene Regulatory Network That Diversifies Neuronal Cell Fates
    The Caenorhabditis elegans Argonautes ALG-1 and ALG-2: Almost Identical yet Different
    MicroRNA Function and Mechanism: Insights from Zebra Fish
    MicroRNAs and Hematopoietic Differentiation
    
    Telomeres and Cancer
    Expression and Suppression of Human Telomerase RNA
    RNA as a Flexible Scaffold for Proteins: Yeast Telomerase and Beyond
    Telomerase RNA Levels Limit the Telomere Length Equilibrium
    
    End Regulation of Transcripts
    Sensing Metabolic Signals with Nascent RNA Transcripts: The T Box and S Box Riboswitches as Paradigms
    Genetic Control by cis-Acting Regulatory RNAs in Bacillus subtilis: General Principles and Prospects for Discovery
    A Mg2+-responding RNA That Controls the Expression of a Mg2+ Transporter
    Structural Studies of the Purine and SAM Binding Riboswitches
    Regulating Bacterial Transcription with Small RNAs
    Turnover and Function of Noncoding RNA Polymerase II Transcripts
    
    RNPs and RNA Editing
    How Does RNA Editing Affect dsRNA-mediated Gene Silencing?
    How a Small DNA Virus Uses dsRNA but Not RNAi to Regulate Its Life Cycle
    Regulation of Two Key Nuclear Enzymatic Activities by the 7SK Small Nuclear RNA
    The SMN Complex: An Assembly Machine for RNPs
    Developing Global Insight into RNA Regulation R.B. Darnell
    Regulation of Alternative Splicing by snoRNAs
    
    Biology of Short RNAs
    Measuring the Rates of Transcriptional Elongation in the Female Drosophila melanogaster Germ Line by Nuclear Run-on
    Polymorphic MicroRNA Target Interactions: A Novel Source of Phenotypic Variation
    Expression and Function of MicroRNAs in Viruses Great and Small
    Expression and Function of MicroRNAs Encoded by Kaposi's Sarcoma-associated Herpesvirus
    Relationship between Retroviral Replication and RNA Interference Machineries
    Positive and Negative Modulation of Viral and Cellular mRNAs by Liver-specific MicroRNA miR-122
    
    Control of Gene Expression by Noncoding RNAs
    The Challenge of Viral snRNPs
    MSL Complex Associates with Clusters of Actively Transcribed Genes along the Drosophila Male X Chromosome
    Noncoding RNAs of the H/ACA Family
    Biogenesis and Intranuclear Trafficking of Human Box C/D and H/ACA RNPs
    RNA and Protein Actors in X-Chromosome Inactivation
    X-Chromosome Kiss and Tell: How the Xs Go Their Separate Ways
    
    Heterochromatin
    Genetic Analyses of DNA Methyltransferases in Arabidopsis thaliana
    RNA-directed DNA Methylation and Pol IVb in Arabidopsis
    Studies on the Mechanism of RNAi-dependent Heterochromatin Assembly
    Cell Biology of the Arabidopsis Nuclear siRNA Pathway for RNA-directed Chromatin Modification
    A Paragenetic Perspective on Integration of RNA Silencing into the Epigenome and Its Role in the Biology of Higher Plants
    RNAi-mediated Heterochromatin Assembly in Fission Yeast
    Slicing and Spreading of Heterochromatic Silencing by RNA Interference
    
    Quality Control， Messenger RNA Turnover， and Translational Control
    Molecular Chaperones and Quality Control in Noncoding RNA Biogenesis
    Stress-induced Reversal of MicroRNA Repression and mRNA P-body Localization in Human Cells
    MicroRNAs Silence Gene Expression by Repressing Protein Expression and/or by Promoting mRNA Decay
    MicroRNAs， mRNAs， and Translation
    Regulation of Poly(A)-binding Protein through PABP-interacting Proteins
    Two Distinct Conformations of the Conserved RNA-rich Decoding Center of the Small Ribosomal Subunit Are Recognized by tRNAs and Release Factors
    Summary: The Expanding Universe ofNoncoding RNAs
    Author Index
    Subject Index