Linkage disequilibrium and association mapping : analysis and applications / edited by Andrew R. Collins. — Totowa : Humana Press, c2007.—(58.17/M592/v.376)

Contents

    Contents
    
    Dedication
    Preface
    Contributors
    1. Linkage Disequilibrium and Association Mapping: An Introduction
    2. A History of Association Mapping
    3. Linkage Disequilibrium Maps and Location Databases
    4. LDMAP: The Construction of High-Resolution Linkage Disequilibrium Maps of the Human Genome
    5. Linkage Disequilibrium as a Tool for Detecting Signatures of Natural Selection
    6. The Genetic Basis of Complex Traits: Rare Variants or "Common Gene， Common Disease"?
    7. Linkage Disequilibrium Mapping for Complex Disease Genes
    8. Linkage Disequilibrium Maps and Disease-Association Mapping
    9. Coalescent Methods for Fine-Scale Disease-Gene Mapping
    10. Family-Based Linkage Disequilibrium Tests Using General Pedigrees
    11. Association Studies Using Familial Cases: An Efficient Strategy for Identifying Low-Penetrance Disease Alleles
    12. Association Mapping Using Pooled DNA
    13. Selecting Single-Nucleotide Polymorphisms for Association Studies With SNPbrowser Software
    14. Avoiding False Discoveries in Association Studies
    15. Gene Mapping in Asthma-Related Traits
    16. Identifying Susceptibility Variants for Type 2 Diabetes