 |
Blood brain barriers : from ontogeny to artificial interfaces / edited by Rolf Dermietzel, David C. Spray, Maiken Nedergaard. — Weinheim : Wiley-VCH , 2006.—(59.52/B655/v. ) |
Contents
Contents
VOLUME 1
Introduction
The Blood-Brain Barrier: An Integrated Concept 1
Rolf Dermietzel， David C. Spray， and Maiken Nedergaard
Part Ⅰ Ontogeny of the Blood-Brain Barrier 9
1 Development of the Blood-Brain Interface 11
Britta Engelhardt
2 Brain Angiogenesis and Barriergenesis 41
Jeong Ae Park， Yoon Kyung Choi， Sae-Won Kim， and Kyu-Won Kim
3 Microvascular Influences on Progenitor Cell Mobilization and Fate in the Adult Brain 61
Christina Lilliehook and Steven A. Goldman
Part Ⅱ The Cells of the Blood-Brain Interface 75
4 The Endothelial Frontier 77
Hartwig Wolburg
5 Pericytes and Their Contribution to the Blood-Brain Barrier 109
Markus Ramsauer
6 Brain Macrophages: Enigmas and Conundrums 129
Frederic Mercier， Sebastien Mambie， and Glenn I. Hatton
7 The Microglial Component 167
Ingo Bechmann， Angelika Rappert， Josef Priller， and Robert Nitsch
8 The Bipolar Astrocyte: Polarized Features of Astrocytic Glia Underlying Physiology， with Particular Reference to the Blood-Brain Barrier 189
N. Joan Abbott
9 Responsive Astrocytic Endfeet: the Role of AQP4 in BBB Development and Functioning 209
Grazia P. Nicchia， Beatrice Nico， Laura M.A. Camassa， Maria G. Mola， Domenico Ribatti， David C Spray， Alejandra Bosco， Maria Svelto， and Antonio Frigeri
Part Ⅲ Hormonal and Enzymatic Control of Brain Vessels 237
10 The Role of Fibroblast Growth Factor 2 in the Establishment and Maintenance of the Blood-Brain Barrier 239
Bernhard Reuss
11 Cytokines Interact with the Blood-Brain Barrier 247
Weihong Pan， Shulin Xiang， Hong Tu， and Abba J. Kastin
12 Insulin and the Blood-Brain Barrier 265
William A. Banks and Wee Shiong Lim
13 Glucocorticoid Hormones and Estrogens: Their Interaction with the Endothelial Cells of the Blood-Brain Barrier 287
Jean-Bernard Dietrich
14 Metalloproteinases and the Brain Microvasculature 313
Dorothee Krause and Christina Lohmann
Part IV Culturing the Blood-Brain Barrier 335
15 Modeling the Blood-Brain Barrier 337
Romdo Cecchelli， Caroline Coisne， Lucie Dehouck， Florence Miller， Marie-Pierre Dehouck， Valerie Buee-Scherrer， and Benedicte Dehouck
16 Induction of Blood-Brain Barrier Properties in Cultured Endothelial Cells 357
Alia Zozulya， Christian Weidenfeller， and Hans-Joachim Galla
17 Artificial Blood-Brain Barriers 375
Luca Cucullo， Emily Oby， Kerri Hallene， Barbara Aumayr， Ed Rapp， and Damir Janigro
18 In Silico Prediction Models for Blood-Brain Barrier Permeation 403
Gerhard F. Ecker and Christian R. Noe
VOLUME 2
Part V Drug Delivery to the Brain 429
19 The Blood-Brain Barrier: Roles of the Multidrug Resistance Transporter P-Glycoprotein 431
Sandra Turcotte， Michel Demeule， Anthony Regina， Chantal Fournier， Julie Jodoin， Albert Moghrabi， and Richard Beliveau
20 Targeting of Neuropharmaceuticals by Chemica Delivery Systems 463
21 Drug Delivery to the Brain by Internalizing Receptors at the Blood-Brain Barrier 501
Pieter J. Gaillard， Corine C. Visser， and Albertus (Bert) G. de Boer
Part VI Vascular Perfusion 521
22 Blood-Brain Transfer and Metabolism of Oxygen 523
Albert Gjedde
23 Functional Brain Imaging 551
Gerald A. Dienel
Part VII Disease-Related Response 601
24 Inflammatory Response of the Blood-Brain Interface 603
Pedro M. Faustmann and Claus G. Haase
25 Stroke and the Blood-Brain Interface 619
Marilyn J. Cipolla 619
26 Diabetes and the Consequences for the Blood-Brain Barrier 649
Arshag D. Mooradian
27 Human Parasitic Disease in the Context of the Blood-Brain Barrier-Effects， Interactions， and Transgressions 671
Mahalia S. Desruisseaux， Louis M. Weiss， Herbert B. Tanowitz， Adam Mort， and Danny A. Milner
28 The Blood Retinal Interface: Similarities and Contrasts with the Blood-Brain Interface 701
Tailoi Chan-Ling
Subject Index 725
