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Metabolomics :methods and protocols /edited by Wolfram Weckwerth.. --Humana Press,2007. –(58.17/M592/v.358) |
Contents
Contents:
1. Metabolite profiling in blood plasma 3
2. nosupervised construction and application of mass spectral and retention time index libraries from time-of flight gas chromatography-mass spectrometry metabolite profiles 19
3. metabolomic profiling of natural volatiles: headspace trapping: CC-MS 39
4. Integrative profiling of metabolites and proteins: improving pattern recognition and biomarker selection for systems level approaches 57
5. Integrative profiling of metabolites and proteins: improving pattern recognition and biomarker selection for systems level approaches 57
6. Visualization and analysis of molecular data 105
7. A gentle guide to the analysis of metabolomic data 105
8. Capillary electrophoresis-Mass spectrometry for metabolomics 129
9. Application of liquid chromatography-Mass spectrometry analysis in metabolomics:reversed-phase monolithic capillary chromatography and hydrophilic chromatography coupled to electrospray lonization-mass spectrometry 141
10. High-performance liquid chromatography separations coupled with coulometric electrode array detectors: a unique approach to metabolomics 159
11. Determination of metabolic flux ratios from13 C-Experiments and gas chromatography-mass spectrometry data: protocol and principles 177
12. Understanding the roadmap of metabolism by pathway analysis 199
13. Revealing the metabolome of animal tissues using 1H nuclear magnetic resonance spectroscopy 229
14. Nuclear magnetic resonance metabonomics: methods for drug discovery and development 247
15. Practical aspects of uniform stable isotope labeling of higher plants for heteronuclear NMR-Based metabolomics 273
