Advances in genetics. v. 54 /edited by Leaf Huang, Mien-Chie Hung, Ernst Wagner. --Elsevier, 2005. -- (58.14/A244/v.54)

Contents

Contents:

1.       The Mechanism of Naked DNA Uptake and Expression  3

2.       Targeted Delivery of Therapeutic Oligonucleotides to Pulmonary Circulation  21

3.       Naked DNA for Liver Gene Transfer  43

4.       Hydrodynamic Delivery  65

5.       Electric Pulse-Mediated Gene Delivery to Various Animal Tissues  83

6.       In Vivo application of RNA Interference: From Functional Genomics to Therapeutics  117

7.       A Novel Gene Expression System: Non-Viral Gene Transfer for Hemophilia as Model Systems  143

8.       Site-Specific Integration with C631 Integrase for Prolonged Expression of Therapeutic Genes  179

9.       Sleeping Beauty Transposon-Mediated Gene Therapy for Prolonged Expression  189

10.   Cancer-Specific Gene Therapy  235

11.   DNA Vaccine  257

12.   Airway Gene Therapy  291

13.   Non-Viral Vector as Vaccine Carrier  315

14.   Non-Viral Vectors for Gene Therapy: Clinical Trials in Cardiovascular Disease  339