首页 > 新书资源
新书资源(2017年10月)

Case studies in cell biology / Merri Lynn Casem. -- London : Academic Press is an imprint of Elsevier, 2016. – (58.15 /C337)

Contents

BIOGRAPHY  xvii

PREFACE  xix

CHAPTER 1      Introduction to scientific method from a cellular perspective  1

Subchapter 1.1 Scientific method in action  1

CHAPTER 2      Cellular biodiversity  11

Subchapter 2.1 Cellular biodiversity on the high seas  11

Subchapter 2.2 The mystery of the missing mitochondria  17

CHAPTER 3      Proteins  23

Subchapter 3.1 Bite of the brown recluse spider: an introduction to protein gel electrophoresis  23

Subchapter 3.2 Where to start? a case of too many AUGs  31

Subchapter 3.3 Cotranslational translocation: gatekeepers of the RER  39

Subchapter 3.4 From sequence to function  47

Subchapter 3.5 Visualizing protein conformation  54

Subchapter 3.6 Second chance chaperones: how misfolded proteins get refolded  62

CHAPTER 4      The nucleus

Subchapter 4.1 Nuclear pore complex assembly is a house of cards  73

Subchapter 4.2 Importin β: the important importin  80

Subchapter 4.3 A tale of tRNA transport  88

Subchapter 4.4 When it comes to the nucleus - size matters  96

CHAPTER 5      Membranes and membrane transport  105

Subchapter 5.1 Flip this lipid  105

Subchapter 5.2 Navigating the bilayer: lipid rafts and caveolae  113

Subchapter 5.3 Shifting gears" calcium transport in flagella  120

CHAPTER 6      Cytoskeleton and intracellular motility  127

Subchapter 6.1 Plakins: keeping the cytoskeleton safe  127

Subchapter 6.2 The moving story of a microtubule motor protein  134

Subchapter 6.3 The WASP and the barbed end  142

Subchapter 6.4 Cilia grow where vesicles go  150

CHAPTER 7      Organelles  157

Subchapter 7.1 Putting the "retic" in the endoplasmic reticulum  157

Subchapter 7.2 How the Golgi stacks up  164

Subchapter 7.3 Case of the coated vesicle  172

Subchapter 7.4 How to build a peroxisome  180

Subchapter 7.5 Putting the squeeze on mitochondAa  187

CHAPTER 8      Exocytosis  193

Subchapter 8.1 Coat proteins and vesicle transport  193

Subchapter 8.2 Endomembrane transport in the absence of a cell  202

Subchapter 8.3 Extra large export: a case for cisternal maturation  209

CHAPTER 9      Endocytosis  217

Subchapter 9.1 Following the fate of a phagosome  217

Subchapter 9.2 Catching a receptor by the tail  224

Subchapter 9.3 Can clathrin bend a membrane?  229

Subchapter 9.4 Modeling membrane fission  235

CHAPTER 10      Cell walls and cell adhesion  241

Subchapter 10.1 Biofilms and Antibiotic Resistance  241

Subchapter 10.2 DIY ECM: cortactin and the secretion of fibronectin  246

Subchapter 10.3 Bundling the brush border  253

CHAPTER 11      Cell metabolism  263

Subchapter 11.1 When glucose is low, something must go  263

Subchapter 11.2 Do plants really need two photosystems?  270

Subchapter 11.3 FREX: opening a window into cellular metabolism  275

CHAPTER 12      Cell signaling  283

Subchapter 12.1 How cells know when it's time to go  283

Subchapter 12.2 Can you "Ad" hear me now? signaling and intraflagellar transport  290

CHAPTER 13      Cell cycle  299

Subchapter 13.1 Now you see it, now you don't: the discovery of cyclin  299

Subchapter 13.2 Sorting out cyclins  305

Subchapter 13.2 Of centriole separation and cyclins  312

Subchapter 13.4 The path to S phase is paved with phosphorylation  319

CHAPTER 14      Cell division  327

Subchapter 14.1 Push and pull: how motor proteins help build a spindle  327

Subchapter 14.2 Ready, set, anaphase!  333

Subchapter 14.3 Building cell walls: cytokinesis in a plant cell  338

CHAPTER 15      Cell systems  345

Subchapter 15.1 Do bumblebees have B cells? a case of insect immunity  345

Subchapter 15.2 What happens when the endosymbionts "bug out"?  353

Subchapter 15.3 Parvovirus: hijacking endocytosis  362

SUBJECT INDEX  373