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Mobile DNA III / editor in chief, Nancy L. Craig ; editors, Michael Chandler ... [et al.]. -- Washington, DC : ASM Press, 2015. – (58.174252/M687/3)

Contents

Contributors    xi

Preface    xxi

I.  INTRODUCTION

1.  A Moveable Feast: An Introduction to Mobile DNA

II. CONSERVATIVE SITE-SPECIFIC RECOMBINATION

2.  An Overview of Tyrosine Site-specific Recombination: From an Flp Perspective    43

3.  The Serine Recombinases    73

4.  The λ, Integrase Site-specific Recombination Pathway

5.  Cre Recombinase    119

6.  The Integron: Adaptation On Demand    139

7.  Xer Site-Specific Recombination: Promoting Vertical and Horizontal Transmission of Genetic Information    163

8.  The Integration and Excision of CTnDOT    183

9.  Site-specific DNA Inversion by Serine Recombinases    199

10.  Serine Resolvases    237

11.  Phage-encoded Serine Integrases and Other Large Serine Recombinases    253

12.  Hairpin Telomere Resolvases    273

13.  Biology of Three ICE Families: SXT/R391, ICEBsl, and ICEStl/ICESt3   289

III. PROGRAMMED REARRANGEMENTS

14.  V(D)J Recombination: Mechanism, Errors, and Fidelity    313

15.  Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination    325

16.  Programmed Genome Rearrangements in Tetrahymena    349

17.  Programmed Rearrangement in Ciliates: Paramecium    369

18.  Programmed Genome Rearrangements in the Ciliate Oxytricha    389

19.  DNA Recombination Strategies During Antigenic Variation in the African Trypanosome    409

20.  Recombination and Diversification of the Variant Antigen Encoding Genes in the Malaria Parasite Plasmodium falciparum    437

21.  Mobile DNA in the Pathogenic Neisseria    451

22.  vls Antigenic Variation Systems of Lyme Disease Borrelia: Eluding Host Immunity through both Random, Segmental Gene Conversion and Framework Heterogeneity    471

23.  Mating-type Gene Switching in Saccharomyces cerevisiae    491

24.  A Unique DNA Recombination Mechanism of the Mating/Cell-type Switching of Fission Yeasts: a Review    515

IV.  DNA-ONLY TRANSPOSONS

25.  Mechanisms of DNA Transposition    531

26.  Everyman's Guide to Bacterial Insertion Sequences    555

27.  Copy-out-Paste-in Transposition of IS911: A Major Transposition Pathway    591

28.  The IS200f1S605 Family and "Peel and Paste" Single-strand Transposition Mechanism    609

29.  Transposons TnlO and Tn5    631

30.  Tn7    647

31.  Transposable Phage Mu    669

32.  The Tn3-family of Replicative Transposons    693

33.  P Transposable Elements in Drosophila and other Eukaryotic Organisms    727

34.  Mariner and the ITm Superfamily of Transposons    753

V.   LTR RETROTRANSPOSONS

35.  bAT Transposable Elements    775

36.  Mutator and MULE Transposons    803

37.  Adeno-associated Virus as a Mammalian DNA Vector    829

38.  Sleeping Beauty Transposition    853

39.  piggyBac Transposon    875

40.  Helitrons, the Eukaryotic Rolling-circle Transposable Elements    893

41.  Tyl LTR-retrotransposon of Budding Yeast, Saccharomyces cerevisiae    927

42.  Ty3, a Position-specific Retrotransposon in Budding Yeast    965

43.  The Long Terminal Repeat Retrotransposons Tfl and Tf2 of Schizosaccharomyces pombe    997

44.  Retroviral Integrase Structure and DNA Recombination Mechanism    1011

45.  Host Factors in Retroviral Integration and Selection of Integration Target Sites    1035

46.  Reverse Transcription of Retroviruses and LTR Retrotransposons

47.  Mammalian Endogenous Retroviruses    1079

48.  Retroviral DNA Transposition: Themes and Variations    1101

VI.  NON-LTR RETROTRANSPOSONS

49.  Integration, Regulation, and Long-Term Stability of R2 Retrotransposons    1127

50.  Site-Specific non-LTR retrotransponsons    1147

51.  The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes    1165

52.  Mobile Bacterial Group II Introns at the Crux of Eukaryotic Evolution    1209

53.  Diversity-generating Retroelements in Phage and Bacterial Genomes    1237

54.  An Unexplored Diversity of Reverse Transcriptases in Bacteria    1253

55.  Tyrosine Recombinase Retrotransposons and Transposons    1271

Index    1293