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Bioinformatics and functional genomics / Jonathan Pevsner. -- 3rd ed. -- Chichester, West Sussex, UK ; Hoboken, NJ, USA : John Wiley and Sons, Inc., 2015. – (58.1423 /P514 /3rd ed.)

Contents

PART I  Analyzing DNA, RNA, and Protein Sequences

1 Introduction, 3

2 Access to Sequence Data and Related Information, 19

3 Pairwise Sequence Alignment, 69

4 Basic Local Alignment Search Tool (BLAST), 121

5 Advanced Database Searching, 167

6 Multiple Sequence Alignment, 205

7 Molecular Phylogeny and Evolution, 245

PART II  Genomewide Analysis of DNA, RNA, and Protein

8 DNA: The Eukaryotic Chromosome, 307

9 Analysis of Next-Generation Sequence Data, 377

10 Bioinformatic Approaches to Ribonucleic Acid (RNA), 433

11 Gene Expression: Microarray and RNA-seq Data Analysis, 479

12 Protein Analysis and Proteomics, 539

13 Protein Structure, 589

14 Functional Genomics, 635

PART III Genome Analysis

15 Genomes Across the Tree of Life, 699

16 Completed Genomes: Viruses, 755

17 Completed Genomes: Bacteria and Archaea, 797

18 Eukaryotic Genomes: Fungi, 847

19 Eukaryotic Genomes: From Parasites to Primates, 887

20 Human Genome, 957

21 Human Disease, 1011

GLOSSARY, 1075

SELF-TEST QUIZ: SOLUTIONS, 1103

AUTHOR INDEX, 1105

SUBJECT INDEX, 1109