Natural biomarkers for cellular metabolism : biology, techniques, and applications / edited by Vladimir V. Ghukasyan, Ahmed A. Heikal. -- Boca RatonL : CRC Press, c2015. – (58.1575/N285) |
Contents
Contents
Series Preface ix
Foreword: Britton Chance--Appreciation xi
Preface
Editors
Contributors.,<br> Abbreviations
SECTION I Biochemical, Biological, and Biophysical Background
1 Mitochondria and Energy Metabolism: Networks, Mechanisms, and Control
2 Intracellular Autofluorescent Species: Structure, Spectroscopy, and Photophysics 41
SECTION II Autofluorescence Imaging Techniques: Fundamentals and Applications
3 One-Photon Autofluorescence Microscopy
4 Autofluorescence Lifetime Imaging
5 Polarization Imaging of Cellular Autofluorescence 107
6 Real-Time In Vivo Monitoring of Cellular Energy Metabolism 137
7 Tryptophan as an Alternative Biomarker for Cellular Energy Metabolism 157
8 Alternative Approaches to Optical Sensing of the Redox State
SECTION III Natural Biomarkers for Biochemical and Biological Studies
9 Spatiotemporal Detection of NADH-Linked Enzyme Activities in Single Cell Metabolism
10 NAD(P)H and FAD as Biomarkers for Programmed Cell Death 215
11 Monitoring Stem Cell Differentiation in Engineered Tissues
SECTION IV Autofluorescence as a Diagnostic Tool in Medicine and Health
12 Autofluorescence-Assisted Examination of Cardiovascular System Physiology and Pathology
13 Autofluorescence Perspective of Cancer Diagnostics
14 Dynamic Imaging of Intracellular Coenzyme Autofluorescence in Intact Pancreatic Islets
15 Autofluorescence Diagnostics of Ophthalmic Diseases
16 Pathogen Effects on Energy Metabolism in Host Cells
Index