Targeted therapies in oncology / edited by Giuseppe Giaccone, Jean-Charles Soria. -- 2nd ed. -- Boca Raton : CRC Press, c2014. – (64.86 /T185 /2nd ed.) |
Contents
CONTENTS
Role of Next-Generation Sequencing Technologies
Siddhartha Devarakonda, Daniel Morgensztern, and Ramaswamy Govindan
Signal Transduction Inhibitors of the HER Family
Christina Brzezniak, Corey Carter, Anish Thomas, and Giuseppe Giaccone
HER2 Inhibition and Clinical Achievements
Berta Sousa, J. Ribeiro, and Fatima Cardoso
Inhibiting the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway
Simona Wagner and Janet E. Dancey
BRAF and MEK Inhibitors
Lidia Robert and Antoni Ribas
KIT and KIT Inhibitors
Jean-Yves Blay, Armelle Dufresne, Olfa Derbel, and Isabelle Ray-Coquard
Targeting the Fibroblast Growth Factor Receptor Pathway in Human Cancer
Maria Vittoria Dieci and Fabrice Andre
Anaplastic Lymphoma Kinase
Aparna Rao and Benjamin Solomon
MET Inhibitors
Apoorva Chawla, Ravi Salgia, and Victoria M. Villaflor
Targeting Stem Cells
Marcello Maugeri-Sacca and Ruggero De Maria
The Cancer Super-Chaperone Hsp90: Its Posttranslational Regulation and Drug Targeting
Annerleim Walton-Diaz, Sahar Khan, Jane B. Trepel, Mehdi Mollapour, and Len Neckers
Targeting Apoptosis Pathways
Pamela M. Holland, David Reese, and Jeffrey Wiezorek
Targeting Angiogenesis
Sophie Postel-Vinay and Jean-Pierre Armand
Antivascular Agents
Gianluca Del Conte and Cristiana Sessa
Immunotherapy: Monoclonal Antibodies (CTLA4, PD-1, PD-L1, IL-18, and IL-21)
Patrick M. Forde and Julie R. Brahmer
Vaccine Therapy and Integration with Other Modalities
Benedetto Farsaci, Peter S. Kim, James W. Hodge, Claudia Palena, James L. Gulley, and Jeffrey Schlom
Histone Deacetylase Inhibitors as Targeted Therapies
Alexandra Zimmer, Arup Chakraborty, Robert W. Robey, and Susan E. Bates
Compounds Targeting Androgen Pathways
Aurelius Omlin, Carmel Pezaro, and Johann de Bono
Targeting DNA Repair: PARP and Chk1 Inhibitors
Peter Stephens and Ruth Plummer
Inhibitors Targeting Mitosis
Dan L. Sackett, Edina Komlodi-Pasztor, and Tito Fojo
Index