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新书资源(2014年12月)

Protein-protein interactions in drug discovery / edited by Alexander Dömling. -- Weinheim : Wiley-VCH, 2013. – (63.32 /P967p)

Contents

    CONTENTS
    
    Protein-Protein Interactions: An Overview
    Prediction of intra- and inter-species protein-protein interactions facilitating systems biology studies
    Modulators of protein-protein interactions: The importance of Three-Dimensionality
    A leap into the chemical space of Protein-Protein Interaction inhibitors
    Interactive technologies for leveraging the known chemistry of anchor residues to disrupt protein interactions
    SH3 Domains as Drug Targets
    P53 MDM2 Antagonists: Towards Non Genotoxic Anticancer Treatments
    Inhibition of LFA-1/ICAM interaction for treatment of autoimmune diseases
    The PIF-binding pocket of AGC kinases: a target site for allosteric modulators and protein-protein interaction inhibitors
    Retosiban and Epelsiban: Potent and Selective Orally available Oxytocin Antagonists
    Peptidic inhibitors of protein-protein interactions for cell adhesion receptors: RGD peptides and beyond
    The REPLACE Strategy for generating Non-ATP competitive Inhibitors of Cell-Cycle Protein Kinases