Protein-protein interactions in drug discovery / edited by Alexander Dömling. -- Weinheim : Wiley-VCH, 2013. – (63.32 /P967p) |
Contents
CONTENTS
Protein-Protein Interactions: An Overview
Prediction of intra- and inter-species protein-protein interactions facilitating systems biology studies
Modulators of protein-protein interactions: The importance of Three-Dimensionality
A leap into the chemical space of Protein-Protein Interaction inhibitors
Interactive technologies for leveraging the known chemistry of anchor residues to disrupt protein interactions
SH3 Domains as Drug Targets
P53 MDM2 Antagonists: Towards Non Genotoxic Anticancer Treatments
Inhibition of LFA-1/ICAM interaction for treatment of autoimmune diseases
The PIF-binding pocket of AGC kinases: a target site for allosteric modulators and protein-protein interaction inhibitors
Retosiban and Epelsiban: Potent and Selective Orally available Oxytocin Antagonists
Peptidic inhibitors of protein-protein interactions for cell adhesion receptors: RGD peptides and beyond
The REPLACE Strategy for generating Non-ATP competitive Inhibitors of Cell-Cycle Protein Kinases