Biomedical sciences : essential laboratory medicine / edited by Ray K. Iles, Suzanne M. Docherty. — Chichester, West Sussex ; Hoboken, NJ : Wiley-Blackwell, 2012. – (61.268/B615e) |
Contents
Contents
List of Contributors
Preface
Chapter 1 Anatomy and physiology of major organ systems
1.1 The skeletal system
1.2 The digestive system
1.3 The cardiovascular system
1.4 The urinary system
1.5 Respiratory system
1.6 The nervous system
1.7 The endocrine system
Bibliography
Chapter 2 Pathophysiology
2.1 Pathophysiology: a definition
2.2 Introduction to epidemiology
2.3 Introduction to pharmacology
2.4 Gastroenterology
2.5 Liver, biliary tract and pancreatic disease
2.6 Rheumatology
2.7 Urinary tract disease
2.8 Cardiovascular disease
2.9 Respiratory disease
2.10 Endocrine disease
Bibliography
Chapter 3 Clinical cell biology and genetics
3.1 The cell
3.2 Genetics
3.3 Human genetic disorders
3.4 Important techniques in molecular cell biology
Bibliography
Chapter 4 Cellular pathology
Part I: Principles of cellular pathology
4.1 Structure and function of normal cells, tissues and organs
4.2 Tissues and organs
4.3 Cellular responses to injury
4.4 Tissue responses to injury: acute inflammation
4.5 Tissue responses to injury: chronic inflammation
4.6 Healing and repair
4.7 Hyperplasia and hypertrophy
4.8 Atherosclerosis
4.9 Thrombosis and embolism
4.10 Ischaemia and infarction
4.11 Amyloid and amyloidosis
4.12 Infections of histological importance
4.13 Metaplasia, dysplasia and carcinoma in situ
4.14 Neoplasia
Part II: Clinical application and laboratory techniques
4.15 Sampling modalities
4.16 Fixation
4.17 Specimen dissection
4.18 Processing and embedding
4.19 Microtomy
4.20 Standard staining methods and procedures
4.21 Frozen section
4.22 Immunohistochemistry
4.23 Cytopathology
4.24 Electron microscopy
4.25 In situ hybridization
Bibliography
Chapter 5 Clinical chemistry
Introduction
Part I: Analytical methods
5.1 Sample collection
5.2 Analytical methods in clinical chemistry laboratories
5.3 Summary: common clinical tests for sample analytes
Part II: Clinical assessments
5.4 Urea and electrolytes (U and Es)
5.5 Metabolism and gastrointestinal markers
5.6 Renal function tests
5.7 Liver function tests
5.8 Heart disease and lipid disorder tests
5.9 Pancreatic function tests
5.10 Bone disease assessment
5.11 Endocrinological assessments
5.12 Pregnancy tests and pregnancy clinical chemistry
5.13 Therapeutic drug monitoring and toxicology
5.14 Clinical chemistry at the extremes of age
5.15 Cancer biomarkers
Bibliography
Chapter 6 Medical microbiology
Introduction
6.1 Overview of microorganisms
6.2 Laboratory investigation of infection
6.3 Bacteria
6.4 Fungi
6.5 Parasitology -- protozoa and helminths
6.6 Viruses
6.7 Prions
6.8 Infections in the immunocompromised patient
6.9 Healthcare associated infections
6.10 Antimicrobial agents
6.11 Vaccines
6.12 Conclusion
Bibliography
Chapter 7 Clinical immunology
Part I: The fundamentals of immunology
7.1 Overview of the immune system
7.2 Overview of the immune response
7.3 MHC genotyping, autoimmunity and susceptibility to disease
7.4 Physical age and immunocompetency
Part II: Laboratory investigations and immune assessments
7.5 Inflammation and chronic infection
7.6 Autoimmune diseases
7.7 Transplant rejection
7.8 Hypersensitivities
7.9 Immune deficiency
Bibliography
Chapter 8 Haematology and transfusion science
8.1 Introduction and components of blood
8.2 Routine laboratory blood tests
8.3 Haemopoiesis
8.4 Red blood cell structure, disorders and metabolism
8.5 Haemoglobin
8.6 Anaemia
8.7 Benign white blood cell disorders
8.8 Haemostasis
8.9 Coagulation disorders
8.10 Myeloproliferative disorders
8.11 Haematological malignancies
8.12 Complement
8.13 Blood transfusion
8.14 Blood products
8.15 Haemopoetic stem cell transplantation
Bibliography
Chapter 9 Professional practice and biomedical science
9.1 What is a biomedical scientist?
9.2 The IBMS
9.3 Professional practice and the role of the HPC
9.4 Standards of proficiency - biomedical scientists
9.5 Expectations of a health professional
9.6 Professional relationships
9.7 The skills required for the application of practice
9.8 Knowledge, understanding and skills
9.9 Standards of conduct, performance and ethics
9.10 CPD
9.11 Critical reflection
9.12 IBMS CPD scheme
9.13 The professional biomedical scientist as an agent for change in the wider healthcare setting
Appendix
Index