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新书资源(2012年4月)

Introducing proteomics : from concepts to sample separation, mass spectrometry and data analysis / Josip Lovric. — Chichester : Wiley-Blackwell, c2011. – (58.17421/L911)

Contents

    Contents
    
    1 Introduction
     1.1 What Are the Tasks in Proteomics?
     1.2 Challenges in Proteomics
     1.3 Proteomics in Relation to Other -omics and System Biology
     1.4 Some General Applications of Proteomics
     1.5 Structure of the Book
     References
    2 Separation and Detection Technologies
     2.1 Introduction to Experimental Strategies in Proteomics
     2.2 Gel-Based Separation
     2.3 Visualization and Analysis of Proteins/Peptides in Gels
     2.4 Gel-Free Separation Technologies
     2.5 Visualization of Proteins/Peptides from Hyphenated Methods
     2.6 Chips in Proteomic Applications
     References
    3 Analysis of Peptides/Proteins by Mass Spectrometry
     3.1 Basic Principles of Mass Spectrometry for Proteomics
     3.2 Ionization Methods for Small Amounts of Biomolecules
     3.3 Mass Analyzers and Mass Spectrometers
     3.4 Concluding Remarks on Mass Analyzers for Proteomics
     References
    4 Analysis and Interpretation of Mass Spectrometric and Proteomic Data
     4.1 Introduction
     4.2 Analysis of MS Data
     4.3 Analysis of MS/MS Data
     4.4 Quantification of LC MS and MS/MS Data from Complex Samples
     4.5 Bioinformatic Approaches for Mass Spectrometric Proteome Data Analysis
     References
    5 Strategies in Proteomics
     5.1 Imaging Mass Spectrometry
     5.2 Qualitative Proteomics
     5.3 Differential and Quantitative Proteomics
     5.4 Analysis of Posttranslational Modifications
     5.5 Interaction Proteomics
     5.6 Proteomics as Part of Integrated Approaches
     References
    Index